ORGANIZATION OF ANTICIPATORY POSTURAL ADJUSTMENTS

预期姿势调整的组织

• 批准号: 2807391
• 负责人: ALEXANDER S ARUIN
• 金额: $ 8.29万
• 依托单位: REHABILITATION FOUNDATION, INC.
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-08-01 至 2003-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2807391
• 关键词: balance; behavioral /social science research tag; clinical research; human subject; posture; proprioception /kinesthesia; psychomotor function

DESCRIPTION (Adapted from the Applicant's Abstract): This proposal will investigate central motor control mechanisms that underlie maintenance of posture. Central control of posture is expressed through anticipatory postural adjustments (APAs) that precede planned postural perturbations and minimize them with anticipatory corrections, and compensatory postural adjustments that deal with actual perturbations of balance that occur because of the suboptimal efficiency of anticipatory corrections. Recently, the Principal Investigator has developed an experimental paradigm for the investigation of anticipatory postural adjustments during self-initiated releasing of a load while standing. The paradigm allows the separation of three major factors that influence APAs: motor action, the effects of external perturbations, and postural stability. Six hypotheses clarifying the organization of anticipatory postural adjustments will be tested in eight experiments. Specific aim 1 will examine the central organization of APAs; Specific aim 2 will independently investigate the effect of each of two factors, motor action and the magnitude of perturbation upon anticipatory postural adjustments. Specific Aim 3 will investigate the effect of postural instability on anticipatory postural adjustments. Specific aim 4 will examine the effect of the relation between motor action and perturbation on anticipatory postural adjustments. It is felt that by understanding the nature of the anticipatory postural adjustments in normal adults one will be better able to understand the loss of control of posture in patients with pathology. Clinical application of the results of the study will define more precisely the focus of conventional rehabilitation strategies aimed at improving postural control in people with postural deficits.

描述(改编自申请人的摘要)：本建议书将 调查作为维护基础的中央电机控制机制 姿势。对姿势的中央控制是通过预期来表达的 在有计划的姿势扰动之前的姿势调整(APA) 并通过预见性纠正和补偿性姿势将其降至最低 处理实际发生的平衡扰动的调整 因为预期修正的效率不是最优的。 最近，首席调查员开发了一种实验 预期性体位调整的研究范式 站着时自发地释放负重。该范例允许 分离影响APA的三个主要因素：运动动作， 外部扰动的影响，以及姿势稳定性。六个假设 澄清预期姿势调整的组织将是 在八个实验中进行了测试。具体目标1将考查中央 《行动纲领》的组织；《特定目标2》将独立调查 两个因素中的每一个的影响，运动动作和运动的大小 对预期姿势调整的干扰。具体目标3将 探讨姿势不稳定对预期姿势的影响 调整。具体目标4将考察这种关系的影响 运动动作和扰动对预期姿势的影响 调整。 人们认为，通过理解预期姿势的性质， 正常成年人的调整将能够更好地理解 病理性患者的体位失控。临床 研究结果的应用将更准确地界定 旨在改进的常规康复战略的重点 有姿势缺陷的人的姿势控制。