Role of Auxiliary Sensory Cues on Balance in Peripheral Neuropathy

描述（由申请人提供）：周围神经病变是一种严重的健康问题。它不仅是糖尿病等常见综合征的结果，而且仍然是衰老过程的重要组成部分。临床神经病变可能导致共济失调、平衡困难和跌倒风险增加。周围神经病变时，感觉线索在姿势和平衡控制中的作用尚不清楚。这项建议的目的是使用一种新的方法，其中辅助感觉线索提供给腿的远端部分的平衡维护中的感觉信息的作用进行研究。PI将评价有和没有辅助感觉提示或踝足矫形器的糖尿病周围神经病变患者的姿势反应变化。该项目将提供关于辅助感觉线索在周围神经病变患者的平衡中所起作用的初步数据。

DESCRIPTION (provided by applicant): Peripheral neuropathy is a significant health problem. It is not only a result of common syndromes such as diabetes, but it also remains a significant part of the aging process. Clinical neuropathies could result in ataxia, balance difficulties, and increased risk of falling. The role of sensory cues in the control of posture and balance in the presence of peripheral neuropathy is unclear. The aim of this proposal is to study the role of sensory information in balance maintenance using a novel approach, in which auxiliary sensory cues are provided to the distal segments of the leg. The PIs will evaluate changes in the postural responses of patients with diabetic peripheral neuropathy with and without auxiliary sensory cues or ankle foot orthoses. The project will provide preliminary data on the role auxiliary sensory cues play in the balance of individuals with peripheral neuropathy.