Role of Auxiliary Sensory Cues on Balance in Peripheral Neuropathy

描述（由申请人提供）：周围神经病变是一个重大的健康问题。它不仅是糖尿病等常见综合征的结果，而且仍然是衰老过程的重要组成部分。临床神经病变可导致共济失调、平衡困难和摔倒风险增加。在周围神经病变的情况下，感觉信号在姿势和平衡控制中的作用尚不清楚。本研究的目的是利用一种新颖的方法研究感觉信息在平衡维持中的作用，该方法将辅助感觉线索提供给腿的远端节段。pi将评估有无辅助感觉提示或踝足矫形器的糖尿病周围神经病变患者的姿势反应变化。该项目将为辅助感觉线索在周围神经病变患者的平衡中所起的作用提供初步数据。

DESCRIPTION (provided by applicant): Peripheral neuropathy is a significant health problem. It is not only a result of common syndromes such as diabetes, but it also remains a significant part of the aging process. Clinical neuropathies could result in ataxia, balance difficulties, and increased risk of falling. The role of sensory cues in the control of posture and balance in the presence of peripheral neuropathy is unclear. The aim of this proposal is to study the role of sensory information in balance maintenance using a novel approach, in which auxiliary sensory cues are provided to the distal segments of the leg. The PIs will evaluate changes in the postural responses of patients with diabetic peripheral neuropathy with and without auxiliary sensory cues or ankle foot orthoses. The project will provide preliminary data on the role auxiliary sensory cues play in the balance of individuals with peripheral neuropathy.