THERAPY DEVELOPMENT FOR FEMALE ADOLESCENT DRUG ABUSE

女性青少年药物滥用的治疗方法开发

• 批准号: 2458487
• 负责人: Gayle Ann Dakof
• 金额: $ 7.1万
• 依托单位: UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-09-30 至 1999-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2458487
• 关键词: adolescence (12-20); behavioral /social science research tag; clinical research; comorbidity; drug /agent; drug abuse therapy; family structure /dynamics; family therapy; female; gender difference; human subject; human therapy evaluation; male; substance abuse related disorder

The proposed study meets the requirements of a small grant (R03) and is submitted under the Behavioral Therapies Development program. It is conceived as a Stage 1 treatment development study. It will take place within the scientific and organizational infrastructure of the Center for Research on Adolescent Drug Abuse, a NIDA-funded treatment evaluation research center. The ultimate objective of the proposed investigation is to increase the effectiveness of drug abuse treatment for adolescent women. It aims to identify clinically relevant concomitants of adolescent drug abuse in females and males, to identify critical factors of success and failure in the treatment of substance abuse in adolescent women, and to establish a foundation for the development of a gender-sensitive family therapy. In Study 1, archived data will be used to gain an understanding of the differences between male and female adolescent substance abusers, predicting that young women referred for treatment will evidence more severe family dysfunction, and higher rates of depression than the males in our study. It's hypothesize that there will be no differences in rates of externalizing disorders. 180 adolescents, 90 females and 90 males, will participate in Study 1. A multiple regression and correlation data analytic strategy will be utilized. Study 2 is an exploratory, hypothesis generating study. It seeks to set a foundation for gender-sensitive interventions with adolescent substance abusers by analyzing the process of family therapy and identifying predictors of success for females as compared with males. Thirty-two adolescents, 16 females and 16 males, with participate in Study 2, which will employ a case analysis methodology to identify essential features of successfully treating drug abuse in adolescent women. The results of the proposed studies should not only increase understanding of young female substance abusers, but also establish avenues for future research designed to assist in developing effective strategies for treating these young people.

拟议的研究满足小额赠款（R03）的要求，并且 根据行为疗法开发计划提交。这是 被视为第一阶段治疗开发研究。它将发生 在该中心的科学和组织基础设施内 青少年药物滥用研究，NIDA 资助的一项治疗评估 研究中心。拟议调查的最终目标是 提高青少年药物滥用治疗的有效性 女性。它的目的是确定青少年的临床相关伴随物 女性和男性滥用药物，以确定成功的关键因素 以及治疗青春期妇女药物滥用的失败，以及 为发展对性别问题有敏感认识的组织奠定基础 家庭治疗。在研究 1 中，存档数据将用于获得 了解男性和女性青少年之间的差异 药物滥用者，预测年轻女性会转诊接受治疗 将证明更严重的家庭功能障碍，以及更高的 在我们的研究中，抑郁症的发生率高于男性。假设会有 外化障碍的发生率没有差异。 180名青少年， 90 名女性和 90 名男性将参加研究 1。 将利用回归和相关数据分析策略。学习 2 是一项探索性假设生成研究。它试图设定一个 对青少年物质进行性别敏感干预的基金会 通过分析家庭治疗的过程并识别施虐者 与男性相比，女性成功的预测因素。三十二 青少年，16 名女性和 16 名男性，参与研究 2，其中 将采用案例分析方法来确定基本特征 成功治疗青春期女性吸毒问题。结果 拟议的研究不仅应该增加对年轻人的了解 女性药物滥用者，同时也为未来的研究奠定了途径 旨在协助制定治疗这些问题的有效策略 年轻人。