THERAPY DEVELOPMENT FOR FEMALE ADOLESCENT DRUG ABUSE

拟议的研究符合小额赠款（R03）的要求， 根据行为疗法发展计划提交。是 作为第1阶段治疗开发研究。它将发生 在该中心的科学和组织基础设施内， 青少年药物滥用研究，NIDA资助的治疗评价 研究中心拟议调查的最终目的是 提高青少年药物滥用治疗的有效性 妇女其目的是确定临床相关的伴随青少年 确定成功的关键因素， 以及对青少年妇女滥用药物治疗失败， 为发展对性别问题敏感的 家庭治疗在研究1中，存档数据将用于获得 了解男女青少年之间的差异 药物滥用者，预测年轻妇女转介治疗， 将证明更严重的家庭功能障碍， 抑郁症的人比我们研究中的男性多据推测， 外化障碍的发生率没有差别。180名青少年， 90名女性和90名男性将参与研究1。多 将采用回归和相关数据分析策略。研究 2是一个探索性的，假设生成的研究。它试图建立一个 对青少年物质采取对性别问题敏感的干预措施基金会 通过分析家庭治疗的过程， 与男性相比，女性成功的预测因素。三十二 青少年，16名女性和16名男性，参与研究2， 将采用案例分析方法来确定基本特征 成功治疗青少年女性的药物滥用。的结果 拟议的研究不仅应该增加对年轻人的了解， 女性药物滥用者，而且还为未来的研究建立了途径 旨在帮助制定有效的战略， 年轻人

The proposed study meets the requirements of a small grant (R03) and is submitted under the Behavioral Therapies Development program. It is conceived as a Stage 1 treatment development study. It will take place within the scientific and organizational infrastructure of the Center for Research on Adolescent Drug Abuse, a NIDA-funded treatment evaluation research center. The ultimate objective of the proposed investigation is to increase the effectiveness of drug abuse treatment for adolescent women. It aims to identify clinically relevant concomitants of adolescent drug abuse in females and males, to identify critical factors of success and failure in the treatment of substance abuse in adolescent women, and to establish a foundation for the development of a gender-sensitive family therapy. In Study 1, archived data will be used to gain an understanding of the differences between male and female adolescent substance abusers, predicting that young women referred for treatment will evidence more severe family dysfunction, and higher rates of depression than the males in our study. It's hypothesize that there will be no differences in rates of externalizing disorders. 180 adolescents, 90 females and 90 males, will participate in Study 1. A multiple regression and correlation data analytic strategy will be utilized. Study 2 is an exploratory, hypothesis generating study. It seeks to set a foundation for gender-sensitive interventions with adolescent substance abusers by analyzing the process of family therapy and identifying predictors of success for females as compared with males. Thirty-two adolescents, 16 females and 16 males, with participate in Study 2, which will employ a case analysis methodology to identify essential features of successfully treating drug abuse in adolescent women. The results of the proposed studies should not only increase understanding of young female substance abusers, but also establish avenues for future research designed to assist in developing effective strategies for treating these young people.