Long-Term Outcomes of Adolescents in Drug Treatment

青少年戒毒治疗的长期结果

• 批准号: 6669119
• 负责人: Gayle Ann Dakof
• 金额: $ 37.88万
• 依托单位: UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-30 至 2007-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6669119
• 关键词: adolescence (12-20); behavioral /social science research tag; clinical research; clinical trials; community mental health services; comorbidity; cost effectiveness; criminal behavior; family structure /dynamics; family therapy; health care service utilization; human subject; human therapy evaluation; job performance; longitudinal human study; mental health services; outcomes research; outpatient care; peer group; residential care facility; substance abuse related disorder

DESCRIPTION: (provided by applicant)Despite impressive recent advances in adolescent drug abuse treatment research, including the manualization and evaluation of theory-based interventions and a preliminary understanding of how these treatments create in-treatment and post-treatment gains, almost nothing is known about the long-term effects of adolescent-specific drug abuse treatment. This application proposes the first controlled long-term study of two state-of-the-science, commonly-practiced treatment modalities -- one outpatient and the other residential -- for adolescent drug abuse. These treatments are being tested in a still active comparative clinical trial being conducted by investigators at the University of Miami Center for Treatment Research on Adolescent Drug Abuse. This ongoing study is the first randomized trial comparing the therapeutic effects and relative benefit-costs of any outpatient approach with a residential adolescent drug treatment. Impressive follow-up data capture rates, promising preliminary 12-month outcome findings from this trial, and the absence of empirical evidence to guide researchers, practitioners or policy makers on the long-term outcomes of adolescent drug treatment all support our aim to study the longer-term impacts of these interventions. The proposed long-term follow-up study will follow 140 adolescents and their parents randomized to either outpatient or residential treatment. Youth and their parents/guardians will be assessed at 2, 3, and 4-year follow-up periods on a range of drug use, family and psychosocial functioning, as well as economic evaluation measures. The study has three aims: 1) To compare the long term effectiveness of residential treatment with outpatient, family-based treatment in ameliorating drug use, co-morbid symptoms, and criminality among dually diagnosed adolescents. 2) To examine the relationships among predictors (i.e., family functioning, peer, educational/vocational functioning and involvement in post-treatment services drug use) and outcome variables (i.e., drug use, co-morbid symptoms, and criminal behavior) during the four-year post intake period. 3) To contrast the total and net long-term monetary benefits of the residential treatment and the outpatient family based treatment.

描述：（由申请人提供）尽管青少年药物滥用治疗研究最近取得了令人印象深刻的进展，包括基于理论的干预措施的手册化和评估以及对这些治疗如何产生治疗中和治疗后收益的初步了解，但对青少年特定药物滥用治疗的长期影响几乎一无所知。该申请提出了针对青少年药物滥用的两种最先进、常用的治疗方式（一种是门诊治疗，另一种是住院治疗）的首次对照长期研究。迈阿密大学青少年药物滥用治疗研究中心的研究人员正在进行一项仍在进行中的比较临床试验，对这些治疗方法进行测试。这项正在进行的研究是第一个随机试验，比较任何门诊方法与住院青少年药物治疗的治疗效果和相对效益成本。令人印象深刻的后续数据捕获率、该试验有望得出的 12 个月初步结果结果，以及缺乏经验证据来指导研究人员、从业者或政策制定者了解青少年药物治疗的长期结果，所有这些都支持我们研究这些干预措施的长期影响的目标。拟议的长期随访研究将跟踪 140 名青少年及其父母，随机接受门诊或住院治疗。青少年及其父母/监护人将在 2 年、3 年和 4 年的随访期接受一系列药物使用、家庭和社会心理功能以及经济评估措施的评估。该研究有三个目的：1) 比较住院治疗与门诊、家庭治疗在改善双重诊断青少年的吸毒、共病症状和犯罪行为方面的长期有效性。 2) 检查吸毒后四年内预测因素（即家庭功能、同伴、教育/职业功能和参与治疗后服务吸毒）和结果变量（即吸毒、共病症状和犯罪行为）之间的关系。 3) 对比住院治疗和门诊家庭治疗的总和净长期货币效益。