BIOSTATISTICS AND DATA MANAGEMENT SECTION

生物统计和数据管理部分

• 批准号: 2456838
• 负责人: S M STEINBERG
• 金额: --
• 依托单位: DIVISION OF CLINICAL SCIENCES - NCI
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/2456838
• 关键词: AIDS therapy; cancer information system; cancer registry /resource; clinical research; clinical trials; data collection methodology /evaluation; diagnosis design /evaluation; drug screening /evaluation; human data; human therapy evaluation; neoplasm /cancer classification /staging; neoplasm /cancer therapy; statistical service /center; statistics /biometry

The Section is the statistical and data management component of the Division of Clinical Sciences (DCS). The Section provides statistical leadership and data management consultation for major activities of the Division, and is involved in the design, conduct, monitoring, and statistical analyses of intramural and national multicenter clinical trials of experimental treatments for cancer, and intramural clinical trials for treatment of AIDS. Other major collaborative efforts include studies to identify important prognostic and treatment selection factors, evaluate diagnostic procedures, develop improved staging systems, and assist investigators in the design, execution, and analyses of major in vitro drug testing studies. The Section develops new statistical designs and biometric methods related to the development and evaluation of new cancer and AIDS treatments. The Section maintains computerized data collection systems for intramural and national multicenter clinical protocols, and it works closely with interested branches to improve data recording and retrieval. The Section is working to develop a comprehensive clinical data base for the DCS and maintains a unified system for tracking basic information on all patients registered on DCS treatment protocols. Approximately 15% of the Sections activities are HIV-AIDS related.

该科是联合国系统的统计和数据管理部门， 临床科学部（DCS）。 该科提供统计数字， 主要活动的领导和数据管理咨询 司，并参与设计，进行，监测， 校内和全国多中心临床研究的统计分析 癌症的实验性治疗试验， 治疗艾滋病的试验。 其他主要合作项目包括 研究以确定重要的预后和治疗选择因素， 评估诊断程序，开发改进的分期系统， 协助研究人员设计，执行和分析主要在 体外药物测试研究。 该科开发新的统计设计 和生物测定方法有关的新的发展和评价 癌症和艾滋病治疗。 该科维持电脑化数据 校内和国家多中心临床试验数据采集系统 协议，并与感兴趣的分支机构密切合作，以改善数据 记录和检索。 该科正在努力制定一个 DCS的综合临床数据库，并维护统一的 用于跟踪在DCS上登记的所有患者的基本信息的系统 治疗方案。 该科约15%的活动 艾滋病相关。