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ALZHEIMER'S DISEASE--PROTEASE ROLE IN NEURONAL DEGENERATION & AMYLOID DEPOSITS

ALZHEIMER'S DISEASE--PROTEASE ROLE IN NEURONAL DEGENERATION & AMYLOID DEPOSITS
阿尔茨海默病——蛋白酶在神经元变性中的作用
批准号：
6098454
负责人：
RALPH A. NIXON
金额：
$12.01万
依托单位：
NATHAN S. KLINE INSTITUTE FOR PSYCH RES
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-07-01 至 2000-06-30
来源：
https://reporter.nih.gov/project-details/6098454
关键词：
Alzheimer's disease Downs syndrome Huntington's disease Parkinson's disease aging amyloid proteins antisense nucleic acid brain disorder diagnosis calpain enzyme activity enzyme mechanism histopathology human tissue immunocytochemistry in situ hybridization isozymes laboratory mouse lysosomes messenger RNA monoclonal antibody neural degeneration neurofibrillary tangles neurofilament proteins northern blottings pathologic process postmortem protease inhibitor protein metabolism protein sequence tissue /cell culture transfection western blottings

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