Mapping the neural circuits which control water and salt intake

绘制控制水和盐摄入量的神经回路

• 批准号: DE190100269
• 负责人: Dr Philip Ryan
• 金额: $ 29.65万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Early Career Researcher Award
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-07-01 至 2023-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DE190100269
• 关键词: Mapping; neural; circuits; control; water

This project aims to map the brain circuits controlling fluid and salt intake using innovative genetically encoded techniques, which enable precise targeting and manipulation of select neuronal populations. Expected outcomes of this project include constructing detailed maps of the brain circuits for fluid and salt intake by tracing multiple nodes in the network, characterising neuronal populations, and precisely defining their functions. This should provide significant benefits including understanding the brain regions controlling fluid and salt intake which are essential for maintaining fluid homeostasis, and providing a framework for investigating the neural circuits underlying other complex behaviours.

该项目旨在使用创新的遗传编码技术绘制控制液体和盐摄入的大脑回路，从而能够精确定位和操纵选定的神经元群体。该项目的预期成果包括通过追踪网络中的多个节点来构建液体和盐摄入的大脑回路的详细地图，表征神经元群体并精确定义其功能。这应该提供显着的好处，包括了解大脑区域控制的液体和盐的摄入量，这是必不可少的维持流体稳态，并提供一个框架，调查神经回路的其他复杂的行为。