MUSCLE SATELLITE CELL WORKSHOP

肌肉卫星细胞工作坊

• 批准号: 2677849
• 负责人: RONALD E ALLEN
• 金额: $ 0.2万
• 依托单位: UNIVERSITY OF ARIZONA
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-09-01 至 1999-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2677849
• 关键词: aging; meeting /conference /symposium; muscle disorder chemotherapy; muscle disorders; muscle satellite cell; myogenesis; regeneration; striated muscles; travel; workshop

DESCRIPTION (taken from the application): The purpose of this conference is to bring together scientists from around the world who are conducting research on skeletal muscle satellite cells. Satellite cells are the postnatal muscle precursor cells that are responsible for normal muscle growth and development, muscle regeneration, and work-induced hypertrophy. During normal fiber growth and in work-induced hypertrophy, satellite cells divide, differentiate and fuse with adjacent fibers; the result is the addition of nuclei to fibers. Following injury to muscle, satellite cells are activated to divide, differentiate and either form new fibers or repair damaged segments of existing fibers. The developmental and physiological circumstances where these activities are important are numerous and range from disease processes, to physical activity, to normal human and animal growth and development. It is stated that there has never been a conference devoted specifically to the biology of muscle satellite cells; research on these cells has been scattered throughout a variety of venues, with primary emphases on cell biology, aging, neuromuscular disease, agriculture or exercise and sports science. As a result, there has been inadequate exchange of information and ideas among scientists that work on satellite cells. The conference will be held August 13 - 16, 1998 in Boston, MA, at the Swissotel. Topics include a keynote lecture the first evening, followed by two and one half days of workshop sessions. There will be an average of two invited speakers per session and the balance of each session will be composed of short, informal research presentations and discussions by participants. Sessions will center on the following topics: (1) origins and lineages of satellite cells, (2) cellular regulation of satellite cells, (3) role of satellite cells in normal muscle growth, (4) role of satellite cells in regenerating muscle, (5) activity of satellite cells in muscle adaptation, exercise and aging, and (5) activity of satellite cells in muscle disease and therapies. The conference will assemble new and established investigators from a variety of sectors within biology in order to exchange ideas, facilitate collaborations and identify significant new issues in satellite cell research.

描述（摘自应用程序）：本次会议的目的是 把来自世界各地的科学家聚集在一起， 骨骼肌卫星细胞的研究。 卫星细胞是 出生后的肌肉前体细胞负责正常的肌肉 生长发育、肌肉再生和工作诱导的肥大。 在正常纤维生长和工作诱导的肥大中，卫星细胞 分裂，分化和融合与相邻的纤维;结果是 核向纤维中的添加。 肌肉损伤后，卫星细胞 被激活以分裂、分化并形成新的纤维或修复 现有光纤的损坏段。 发育和生理 这些活动很重要的情况很多，范围很广， 从疾病过程，到身体活动，再到正常的人类和动物， 促进经济增长和发展。 据说，从来没有一次会议专门讨论 肌肉卫星细胞的生物学;对这些细胞的研究已经 分散在不同的场地，主要侧重于细胞 生物学、衰老、神经肌肉疾病、农业或锻炼和体育 科学 因此，信息交流不足， 研究卫星细胞的科学家们的想法。 会议将 1998年8月13日至16日在马萨诸塞州波士顿的瑞士酒店举行。 主题包括A 主题演讲的第一个晚上，其次是两天半的 研讨会。 每届会议平均邀请两名发言人。 每届会议的其余部分将由简短的非正式会议组成。 参与者的研究报告和讨论。 会议将 围绕以下几个问题展开：（1）卫星的起源和谱系 细胞，（2）卫星细胞的细胞调节，（3）卫星的作用 正常肌肉生长中的细胞，（4）卫星细胞在再生中的作用 肌肉，（5）卫星细胞在肌肉适应、运动和 衰老，和（5）肌肉疾病和治疗中卫星细胞的活性。 会议将聚集来自一个新的和建立的调查人员， 生物学内的各种部门，以交流思想，促进 协作，并确定卫星小区的重大新问题 research.