THIRD INTERNATIONAL SYMPOSIUM ON HORMONAL CARCINOGENESIS

申请人的描述（Applicant's Description） 激素致癌作用国际研讨会已成为 美国和外国研究人员研究的首要国际论坛 激素和其他生长调节剂在启动中的作用， 促进和激素癌症的进展。 许多这些肿瘤， 即乳腺、前列腺、卵巢和子宫内膜，代表了一些 最常见的癌症在人类中蔓延。 这些研讨会是独一无二的， 他们聚集了一群流行病学家，基础科学家， 广泛不同学科的临床医生，包括细胞和分子 生物学，内分泌学，生物化学，生殖毒理学，病理学， 妇科医学和流行病学 特邀发言人参加了 癌症研究的前沿 第三次研讨会将与弗雷德哈钦森合作举行 癌症研究中心，并将在其设施在西雅图，华盛顿州， 1998年9月6日至12日。 主要会议包括：（1）人口/分子 乳腺癌、前列腺癌和卵巢癌的流行病学研究;（2） 激素致癌部位的分子遗传学研究;（3）雌激素受体 在人类和动物模型中的相互作用;（4）雌激素/孕激素在 乳腺癌;（5）乳腺癌和乳腺癌细胞周期和细胞增殖研究 子宫内膜癌;（6）癌基因和抑制基因;（7）芳香化酶： 乳腺癌的含义;和（8）器官部位：前列腺和卵巢。 研讨会和最先进的讲座将由杰出的 研究人员对与激素致癌作用有关的主题进行了研究。 的 临床会议将集中在激素的好处和风险， 雌激素替代疗法（HRT，ERT）在女性。 基础和临床 研究报告将在本次会议上提交。 由于全面和 综合形式，这些研讨会已成为唯一的国际论坛 传播该领域的最新进展，提供更广泛的 通过及时在书中出版会议记录来公开信息 form.

DESCRIPTION (Applicant's Description) The International Symposia on Hormonal Carcinogenesis have become the premier international forum for both USA and foreign researchers studying the role of hormones and other growth regulators in the initiation, promotion, and progression of hormonal cancers. Many of these neoplasms, namely, breast, prostate, ovarian, and endometrial, represent some of the most prevalent cancers Occurring in humans. These Symposia are unique in that they bring together a group of epidemiologists, basic scientists, and clinicians of widely diverse disciplines, including cell and molecular biology, endocrinology, biochemistry, reproductive toxicology, pathology, gynecology, medicine, and epidemiology. Invited speakers are engaged in the cutting edge of hormone-associated cancer research. The Third Symposium will be held in cooperation with the Fred Hutchinson Cancer Research Center and will take place in its facilities in Seattle, WA, September 6-12,1998. Major sessions include: (1) Population/molecular epidemiologic studies of breast, prostate, and ovarian cancers; (2) Molecular genetic studies of hormonal cancer sites; (3) Estrogen receptor interactions in human and animal models; (4) Estrogen/progesterone action in breast cancer; (5) Cell cycle and cell proliferation studies in breast and endometrial cancers; (6) Oncogenes and suppressor genes; (7) Aromatase: Implications for breast cancer; and (8) Organ sites: Prostate and ovary. Symposium and State-of-the-Art lectures will be presented by outstanding investigators on subjects pertinent to hormonal carcinogenesis. The clinical session will focus on the benefits and risks of hormone and estrogen replacement therapy (HRT, ERT) in women. Both basic and clinical studies will be presented in this session. Because of the comprehensive and integrated format, these Symposia have become the sole international forum for dissemination of the latest advances in the field, providing a wider exposure of information by the timely publication of the proceedings in book form.