FASEB CONFERENCE--FOLATE, B12 AND ONE CARBON METABOLISM

请拨资金为第七届FASE B夏季会议提供部分支助 叶酸、维生素B12和一碳研究会议 新陈代谢，将在美国联合会的赞助下举行 美国实验生物学学会(FASE B)1998年8月1日至8月6日 科罗拉多州的斯诺马斯村。这次会议提供了一个独特的 临床科学家、基础科学家和那些 参与科学政策的学科范围广泛，具有 对叶酸、维生素B12和一种碳代谢感兴趣 正式和非正式的互动。最近五次会议都有 已全额订阅，参加本次会议的人数将为 限制为180个人。需要资金才能让毕业生 学生、住院医生和博士后研究员，并建立国家 和国际科学家出席会议。详细的计划 其中包括知名科学家和初级科学家 科学家们刚刚进入这一领域。此外，主题还扫描整个 从当前的临床问题到最重要的领域 尖端的生化和生物物理研究。会议一直在进行 一碳代谢计划：酶学和调控； 同型半胱氨酸代谢和调节；蛋氨酸和叶酸辅助因子 作为合成/调节；甲基转移、DNA、修复和 致癌；叶酸和维生素的细胞和上皮运输 叶酸依赖的酶反应；叶酸、维生素B12和 中枢神经系统：发育、衰老和认知；叶酸和B12 合成，化疗的新靶点；以及遗传异质性和 叶酸和维生素B12的要求。除了正式的 除了演讲，该计划还将辅之以海报会议和 研讨会。这些活动提供了许多非正式讨论和 允许研究生、住院医生和博士后研究员以及 知名科学家，有机会介绍和讨论他们的 工作。与过去一样，最有趣的新研究在 会议将以以下形式向更广泛的受众传播 一篇或多篇发表在FASE期刊上的“最新”评论。

Funds are requested for partial support of the Seventh FASEB Summer Research Conference on Folic Acid, Vitamin B12 and One Carbon Metabolism, to be held under the auspices of the Federation of American Societies for Experimental Biology (FASEB) from August 1- August 6, 1998 at Snowmass Village, Colorado. This conference offers a unique opportunity for clinician scientists, basic scientists, and those involved in science policy from a broad group of disciplines with an interest in folic acid, vitamin B12 and one carbon metabolism, to interact both formally and informally. The last five conference have been fully subscribed and participation at this conference will be limited to 180 individuals. Funds are requested to allow graduate students, residents and postdoctoral fellows and established national and international scientists to attend the meeting. A detailed program is presented which includes well established scientists and junior scientists just entering the field. In addition, topics scan the entire spectrum from current clinical problems to areas of the most sophisticated biochemical and biophysical research. Sessions have been scheduled on one carbon metabolism: enzymology and regulation; homocysteine metabolism and regulation; methionine and folate cofactor as synthesis/regulation; methyl transfer, DNA, repair and carcinogenesis; cellular and epithelial transport of folate and vitamin B 12; folate dependent enzyme reactions; folate, vitamin B12, and the central nervous system: development aging, and cognition; folate and B12 synthesis, new targets for chemotherapy; and genetic heterogeneity and folate and vitamin B12 requirements. In addition to the formal presentations, the program will be complemented with poster sessions and workshops. These offer many opportunities for informal discussion and allow graduate students, residents and postdoctoral fellows, as well as established scientists, an opportunity to present and discuss their work. As in the past, the most interesting new research presented at the conference will be disseminated to a much wider audience in the form of one or more "state-of-the-art" reviews in the FASEB Journal.