HEALTH RELATED QUALITY OF LIFE IN CHILDHOOD CANCER

儿童癌症患者的健康相关生活质量

• 批准号: 2665667
• 负责人: RAYMOND K MULHERN
• 金额: $ 1万
• 依托单位: ST. JUDE CHILDREN'S RESEARCH HOSPITAL
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-06-01 至 1999-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2665667
• 关键词: meeting /conference /symposium; neoplasm /cancer therapy; pediatric neoplasm /cancer; quality of life; travel

DESCRIPTION (Applicant's Description) There is a critical need for the development of valid and useful measures of health-related quality of life (HRQL) for children with cancer. The ever-increasing survival rates in pediatric oncology, presently approaching 70 percent overall, demand that priorities be modified to not only seek cure but to also focus close attention on the HRQL costs of cure. Key elements of the cost of cure include the morbidity associated with short-term and long-term toxicities, and the morbidity associated with the sequelae of the disease itself. A critical issue in designing new clinical trials for childhood cancer is how to reduce the morbidity of treatment without compromising survival. These morbidities can now be quantified objectively with newly emerging measures of HRQL. Measuring HRQL of patients during the process of treatment would provide information helpful to patients, families, and health-care providers faced with difficult decisions about treatment alternatives. Similarly, HRQL information on long-term survivors would help to inform decision-making at the time of diagnosis. However, further substantive progress requires the identification, acceptance, and use of validated HRQL measures. The primary aim of the proposed international scientific workshop, "Assessing Health-Related Quality of Life in Childhood Cancer," is to advance the accumulation and exchange of information on the measurement of HRQL in the context of cancer during childhood. Each of six specific objectives of the workshop will be addressed in a separate session by, 3 to 5 invited speakers chosen on the basis of submitted abstracts. In addition, invited discussants will provide a integrative summary of the field and define potential future directions to the participants on the final day. All presentations will be published in full manuscript format as a supplement to the International Journal of Cancer.

描述(申请人的描述)非常需要 制定与健康相关的生活质量的有效和有用的测量 (HRQL)适用于癌症儿童。中国不断增长的存活率 儿科肿瘤学，目前总体接近70%，要求 修改优先事项，不仅要寻求治愈，而且要密切关注 关注治疗的HRQL成本。治愈成本的关键要素 包括与短期和长期毒性相关的发病率， 以及与疾病本身的后遗症相关的发病率。一个 设计儿童癌症新临床试验的关键问题是如何 在不影响生存的情况下减少治疗的发病率。这些 现在可以用新出现的措施来客观地量化疾病 HRQL.在治疗过程中测量患者的HRQL将 为患者、家属和医疗保健提供者提供有用的信息 面临着关于治疗替代方案的艰难决定。同样， HRQL关于长期幸存者的信息将有助于决策 在确诊的时候。然而，进一步取得实质性进展需要 确认、接受和使用有效的HRQL措施。这个 拟议的国际科学讲习班的主要目的是“评估 儿童癌症患者的健康相关生活质量“是为了提高 关于高质量生活质量测量的信息积累和交流 儿童时期患癌症的背景。六个具体目标中的每一个 研讨会将在单独的会议上由3至5名特邀演讲者发言 根据提交的摘要进行选择。此外，还邀请 讨论者将提供该领域的综合总结，并定义 在最后一天为参与者指明未来的潜在方向。全 演示文稿将以全文形式出版，作为对 《国际癌症杂志》。