CONFERENCE ON ENDOTHELIUM

描述：(改编自应用)内皮细胞调节 细胞(例如，白细胞和癌细胞)、大分子(例如， 蛋白质、脂蛋白)、溶质(例如糖、电解质)和水 在血管内腔和血管外腔之间。血管内皮细胞 特定的血管段(例如，动脉、毛细血管后小静脉)，以及 组织(如脑、肺、肾)表现出结构性和功能性 这些解剖部位特有的专门化。这次会议 将探索调控的基本细胞和分子机制 这些专业化以及各种环境 因素和应激刺激(例如，低氧、趋化因子、细胞因子、天然 以及改变的基底膜蛋白、血管生成和血管抑制因子， 天然和修饰的脂蛋白，活化的白细胞，癌细胞，异种 和同种异体器官移植)，影响内皮细胞结构和 功能。在所有这些方面的知识都有了实质性的进步 在过去的几年里，这些地区。通过同时安排此会议与 《白细胞贩运的分子机制》会议主办方 为调查人员之间的多学科交流创建了一个论坛 研究白细胞和内皮细胞的基础和应用方面 生物学，同时为他们保留参加会议的机会 以及与他们自己的研究特别相关的研讨会。

DESCRIPTION: (Adapted from the application) Endothelial cells regulate the movement of cells (e.g., leukocytes and cancer cells), macromolecules (e.g., proteins, lipoproteins), solutes (e.g., sugars, electrolytes), and water between intra- and extra-vascular compartments. Endothelial cells in specific vascular segments (e.g., artery, post-capillary venule), and tissues (e.g., brain, lung, kidney) exhibit structural and functional specializations characteristic of these anatomic locations. This meeting will explore the fundamental cellular and molecular mechanisms that regulate these specialization's and the pathways by which a variety of environmental factors and stressful stimuli (e.g., hypoxia, chemokines, cytokines, native and altered basement membrane proteins, angiogenic and angiostatic factors, native and modified lipoproteins, activated leukocytes, cancer cells, xeno- and allogeneic organ transplantation), affect endothelial cell structure and function. There have been substantial advances in knowledge in all of these areas in the past few years. By scheduling this meeting concurrently with the meeting "Molecular Mechanisms of Leukocyte Trafficking" the organizers have created a forum for multidisciplinary exchange between investigators working on basic and applied aspects of leukocyte and endothelial cell biology, while preserving opportunities for them to participate in sessions and workshops of special relevance to their own research.