RESONANCE RAMAN STUDIES OF RHODOPSIN AND RELATED PIGMENTS

这项研究的总体目标是研究光的机制 视觉色素及相关色素中的能量传递 共振拉曼光谱。这项技术是一项非常强大的技术 探索视觉色素的结构及其结构变化 伴随着视力早期阶段的视网膜生色团。这个 最终目标是从分子的角度理解光是如何 能量被转化为被称为视觉传导的化学物质。 转导过程是生物学中的重要问题，而分子 了解视觉系统是重要的一步。 设想了三个主要的研究领域。实验计划是为了 阐明发色部位的性质。的结构。 初级感光产品要进行测量，以便了解光如何 能量被转化为化学能。最后，暗中间体和 要探索反应途径，以帮助阐明这种化学物质是如何 使用的是能量。

The overall goal of this research is to study the mechanism of light energy transduction in visual pigments and related pigments using resonance Raman spectroscopy. This technique is a very powerful one to probe the structure and changes in structure of the visual pigment retinal chromophore that accompany the early stages of vision. The ultimate goal is to understand from a molecular viewpoint how light energy is converted to that chemistry that is called visual transduction. Transduction processes are important problems in biology, and a molecular understanding of the visual system is an important step. Three main areas of study are envisioned. Experiments are planned to elucidate the nature of the chromophoric site. The structure of the primary photoproducts are to be measured so as to understand how light energy is converted to chemical energy. Lastly, dark intermediates and reaction pathways are to be probed to help elucidate how this chemical energy is used.