BIOINORGANIC CHEMISTRY OF MANGANESE ENZYMES

锰酶的生物无机化学

• 批准号: 2684064
• 负责人: G CHARLES DISMUKES
• 金额: $ 0.8万
• 依托单位: UNIVERSITY OF GRENOBLE I
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-03-17 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/2684064
• 关键词: catalase; chelating agents; chemical synthesis; chemistry; electron spin resonance spectroscopy; manganese; metal complex; photosynthetic reaction centers; spectrometry; training

The long-term objectives of the proposed training program are to expand the research skills of the principal investigator in two areas during an upcoming sabbatical leave. Acquisition of these new research skills will enable new opportunities for improved insight into the principal investigators current NIH-funded research projects. This experience will be transferred to the students and postdoctoral collaborators in the principal investigator's laboratory. Specific skills will be acquired in the application of rapid mixing spectrophotometry to enzymatic reactions, and the synthesis of asymmetric difunctional chelating ligands for use in metal ion coordination chemistry and catalysis.

拟议培训方案的长期目标是 将首席调查员的研究技能扩展到两个方面 在即将到来的休假期间。收购这些新产品 研究技能将为提高洞察力提供新的机会 主要调查人员目前由NIH资助的研究 项目。这一经历将传递给学生和 首席研究员的博士后合作者 实验室。将在应用中获得特定的技能 酶促反应的快速混合分光光度测定法 不对称双官能团络合配体的合成 金属离子配位化学与催化。