Potential of gene drives to eliminate incursions of Drosophila suzukii

本项目旨在测试不同类型基因驱动的功效和进化稳定性，并模拟基因驱动是否可以用于消除铃木果蝇入侵澳大利亚。现在有可能使用基因组编辑技术通过“基因驱动”来改变生物体的种群。人们设想了多种策略，其中主要区别在于那些旨在消灭种群的策略和那些旨在改变种群的策略。该项目将在两种蝇类中研究这些策略，即模型果蝇黑腹果蝇和破坏园艺的害虫铃木果蝇。该项目预计将评估一种基因驱动策略，以控制威胁澳大利亚软皮水果产业的入侵害虫。

This project aims to test the efficacy and evolutionary stability of different types of gene drives, and model whether gene drives can be used to eliminate incursions of Drosophila suzukii into Australia. It is now possible to use genome editing technology to alter populations of organisms using ‘gene drives’. Multiple strategies have been conceived with a major distinction between those that aim to eliminate populations versus those that aim to modify populations. This project will examine these strategies in two fly species, the model, Drosophila melanogaster and the devastating pest of horticulture, Drosophila suzukii. The project expects to assess a gene drive strategy to control the invasive pest that threatens the Australian soft-skinned fruit industries.