COORDINATION DYNAMICS OF HUMAN BRAIN AND BEHAVIOR

这是对ADAMHA高级科学家奖(KO5)的申请。这个 我的实验和理论工作的广泛目标是 了解神经系统如何协调其许多程度的 服务于行为功能的自由。工作的重点是 关于说明内部协调的机制和原则 人类的大脑，以及大脑和行为之间，仔细地使用 选定的一套范例。这种方法有三个方面，结合起来： 1)自组织的理论概念和工具；2) 具有显著分叉特征的实验模型系统； 以及3)先进的技术，能够分析大脑的 时空活动。为此，我有幸有机会 CTF系统公司的全头神经磁成像设备， 温哥华，博卡拉顿的功能性和常规核磁共振设施， 与和我有共同兴趣的杰出理论家直接接触。 RSA将解除我的教学和行政职责，并 请允许我花时间收集和分析实验 数据。RSA还将使我能够加深对 神经科学、建模和计算物理，以获得 更深入地了解大脑结构和 功能。我期待着这些研究和科学进步 活动至少会占用我85%的时间。使用RSA，我还 计划继续我在指导和科学教育方面的积极作用。 L将继续领导我们的NIMH复杂系统培训项目 并提供研究经验和指导 给博士后和博士后。最后，我打算留下来 活跃在南佛罗里达社区，促进科学和 向公众阐明其目标，特别是在 与人类大脑与行为的关系有关。

This is a request for an ADAMHA Senior Scientist Award (KO5). The broad objective of my experimental and theoretical work is to understand how the nervous system orchestrates its many degrees of freedom in the service of behavioral function. The work is focused on illustrating the mechanisms and principles of coordination within the human brain, and between the brain and behavior, using a carefully selected set of paradigms. The approach is three pronged, combining: 1) theoretical concepts and tools of self-organization; 2) experimental model systems in which bifurcations feature prominently; and 3) advanced technologies that enable the analysis of the brain's spatiotemporal activity. To this end I am fortunate to have access to a full-head, neuromagnetic imaging device at CTF Systems, Vancouver, functional and conventional MRI facilities in Boca Raton, and direct contact with eminent theoreticians who share my interests. The RSA will release me from teaching and administrative duties and allow me to spend the time needed to collect and analyze experimental data. The RSA will also enable me to enhance my understanding of neuroscience, modeling and computational physics, in order to gain deeper insight into the connection between brain structure and function. I expect these research and scientific enhancement activities will consume at least 85% of my time. With the RSA, I also plan to continue my active role in mentoring and science education. l shall continue to lead our NIMH Training Program in Complex Systems and Brain Sciences and to provide research experience and mentoring to predoctoral and postdoctoral students. Finally, I intend to remain active in the South Florida community, promoting science and articulating its goals to the general public, particularly as it relates to the human brain-behavior relation.