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HLA CLASS II ANTIGEN PRESENTATION DURING VIRAL INFECTION

HLA CLASS II ANTIGEN PRESENTATION DURING VIRAL INFECTION
病毒感染期间 HLA II 类抗原呈递
批准号：
2671417
负责人：
NEAL R NYGARD
金额：
$8.75万
依托单位：
UNIVERSITY OF ILLINOIS AT CHICAGO
依托单位国家：
美国
项目类别：
财政年份：
1996
资助国家：
美国
项目状态：
已结题
起止时间：
1996-08-01 至 2000-07-31
来源：
https://reporter.nih.gov/project-details/2671417
关键词：
MHC class II antigen T lymphocyte antigen presentation antigen presenting cell human tissue influenza influenzavirus A peptide chemical synthesis recombinant proteins synthetic peptide tissue /cell culture virus antigen virus protein

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英文摘要
DESCRIPTION: The principal investigator proposes to investigate the structure and intracellular trafficking of HLA class II binding peptides originating from viral and endogenous proteins during influenza infection. The objectives of the study are to: (1) characterize naturally processed influenza peptides bound to HLA class II molecules, (2) examine the trafficking and processing of cytosolic influenza proteins in the class II presentation pathway, and (3) assess the effect of influenza infection on the binding of self peptides to class II molecules.
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HLA CLASS II ANTIGEN PRESENTATION DURING VIRAL INFECTION
  • 批准号：
    2057698
  • 项目类别：
  • 资助金额：
    $4.83万
  • 财政年份：
    1996
  • 负责人：
    NEAL R NYGARD
  • 依托单位：
    UNIVERSITY OF VIRGINIA
HLA CLASS II ANTIGEN PRESENTATION DURING VIRAL INFECTION
HLA CLASS II ANTIGEN PRESENTATION DURING VIRAL INFECTION
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