ACTIVATED SODIUM CHANNELS IN HYPERTENSION

高血压中的激活钠通道

• 批准号: 2701258
• 负责人: DAVID Gene WARNOCK
• 金额: $ 22.84万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-05-01 至 2001-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2701258
• 关键词: B lymphocyte; RNase protection assay; Xenopus oocyte; amiloride; angiotensin /renin /aldosterone hypertension; clinical research; cyclic AMP; dietary sodium; family genetics; human subject; insulin; nutrition related tag; pathogenic diet; polymerase chain reaction; protein kinase C; renal tubular transport; single cell analysis; sodium channel; tissue /cell culture; voltage /patch clamp

DESCRIPTION (Adapted from the Applicant's Abstract): This grant has three Specific Aims: Electrophysiologic studies of the activated Na+ channel phenotype in B lymphocytes from patients with hypertension, the expression of the Na+ channel phenotype in the oocyte expression system, and expression studies and cloning of the B lymphocyte Na+ channel subunits.

描述（改编自申请人摘要）：本基金包括三个项目