DETERMINATIONS OF CANNABINOIDS IN MECONIUM

通过吸毒将滥用药物传播给婴儿 在一个获得胎粪的州项目中对怀孕进行监测 从医院选出的代表不同阶层的新生儿 在整个人口中。出乎意料的高阳性率 四氢大麻素类化合物的结果需要进一步分析 保留的先前检查的胎粪样本的剩余部分 以确定标准方法(FPIA)是否给出假阳性。 一种质谱学方法被设计出来，类似于发表的 方法，但进行了修改以处理存储的样本。质谱学 方法显示总有效率较低。所取得的成果已经 由专门研究这种类型的商业实验室验证 化验和最近收集的进一步样本已提交用于 分析。

Transmission of abused drugs to infants through drug use during pregnancy is being monitored in a state program that obtains meconium from newborns in hospitals selected to represent the various strata among the whole population. Unexpectedly high rates of positive results for tetrahydrocannabinoids has necessitated further analysis of the reserved remainder of thepreviously examined meconium samples to determine whether the standard method (FPIA) gives false positives. A mass spectrometric method was devised, similar to a published method, butmodified to handle stored samples. The mass spectrometric method indicated a lower overall rate. Results obtained have been verified by a commercial laboratory that specializes in this type of assay and further recently collected samples have been submitted for analysis.