Evolution and specificity of alternative splicing in plants

植物选择性剪接的进化和特异性

• 批准号: DP190101479
• 负责人: Prof Sureshkumar Balasubramanian
• 金额: $ 29.5万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-01-01 至 2023-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP190101479
• 关键词: Evolution; specificity; alternative; splicing; plants

This project aims to elucidate fundamental principles of alternative splicing, a basic mechanism that plays a vital role in several biological processes across all organisms. Plants are highly effective in adapting to varied environmental, seasonal and climatic conditions and this project aims to uncover how alternative splicing contributes to regulation of gene expression in response to developmental and environmental cues. Uncovering the underlying mechanisms of alternative splicing will not only advance fundamental knowledge, but also has the potential to provide tools and technologies through which sensitivities of plants to environmental stress can be potentially manipulated to benefit agriculture.

该项目旨在阐明选择性剪接的基本原理，这是一种在所有生物体的几个生物过程中发挥关键作用的基本机制。植物在适应不同的环境、季节和气候条件方面非常有效，这个项目旨在揭示选择性剪接如何有助于调节基因表达，以响应发育和环境提示。揭示选择性剪接的潜在机制不仅将促进基础知识的发展，还有可能提供工具和技术，通过这些工具和技术可以潜在地操纵植物对环境胁迫的敏感性，从而使农业受益。