Outlines to outcomes : Second-generation AI auto-contouring for radiotherapy

结果概述：用于放射治疗的第二代人工智能自动轮廓

• 批准号: 830253
• 金额: $ 74.34万
• 依托单位: MIRADA MEDICAL LIMITED
• 依托单位国家: 英国
• 项目类别: Innovation Loans
• 财政年份: 2021
• 资助国家: 英国
• 起止时间: 2021 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=830253
• 关键词: Outlines; outcomes; Second; generation; AI

External Beam Radiotherapy (RT) is a cornerstone of modern cancer treatment and is offered to 50% of cancer patients in the UK. RT planning involves manually outlining the target to be irradiated and healthy tissues and organs to be avoided on medical images of the patient (such as CT scans). This planning is time-consuming and skill-intensive, and there is inevitable inter- and intra-observer variation. Technology to automatically contour (auto-contouring) organs can reduce variability and improve efficiency of the contouring process. Following on from a previous project funded by InnovateUK, Mirada Medical, as an established developer of innovative software in RT planning, was first-to-market with their CE marked AI-based auto-contouring solution, DLCExpert. With the use of DLCExpert, clinicians can contour organs-at-risk faster and more consistently than with manual contouring reducing the time required for treatment planning and allowing patients to be treated sooner.While substantially better than the previous class of technology, the AI solutions available on the market are first generation and still have room for improvement, with editing of the contours produced still being required in many instances. AI technology could be considered to still be in its infancy. In this project, we seek to further advance the state-of-the-art, pushing towards a second-generation solution which would represent another step change in performance and lead to auto-contouring that requires no manual adjustment, thus providing further time-saving in the cancer treatment pathway.

外束放射疗法（RT）是现代癌症治疗的基石，并提供给英国50％的癌症患者。 RT规划涉及手动概述要受辐照的目标以及健康的组织和器官，以避免使用患者的医学图像（例如CT扫描）。该计划是耗时且技能密集的，并且不可避免地存在与观察者内部和内部的变化。自动轮廓（自动包含）器官的技术可以降低变异性并提高轮廓过程的效率。继Innovateuk先前资助的项目之后，Mirada Medical作为RT计划中创新软件的既定开发商，首次是市场上的市场，其CE标记为基于AI的自动包含解决方案DLCEXPERT。借助DLCEXPERT，临床医生可以比手动轮廓减少治疗计划所需的时间并让患者更快地进行治疗的时间更快，更稳定地轮廓器官，但比以前的技术要好得多，但AI在市场上的AI解决方案仍然是第一代的AI Solutions，并且仍然可以改进并且需要改进，并且还需要编辑许多工具，并且需要进行许多工具。可以认为AI技术仍处于起步阶段。在这个项目中，我们试图进一步推进最先进的方法，朝着第二代解决方案迈进，这将代表性能的另一步骤变化，并导致无需手动调整的自动载体，从而为癌症治疗途径提供了进一步的时间储蓄。