TREATMENT OF ENDOTHELIAL DYSFUNCTION

内皮功能障碍的治疗

• 批准号: 6281896
• 负责人: ANDREW Peter SELWYN
• 金额: $ 4.73万
• 依托单位: BRIGHAM AND WOMEN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-12-01 至 1998-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6281896
• 关键词: acetylcholine; antihypercholesterolemic agent; cardiovascular disorder chemotherapy; clinical research; clinical trials; coronary artery; coronary disorder; human subject; human therapy evaluation; vascular endothelium; vasodilation; vasomotion

This protocol will study whether abnormal coronary vasomotion can be reversed by therapy to lower cholesterol. Restoration of endothelial funcion will be represented by the return of endothelium-dependent dilation to acetylcholine with the reversal of paradoxical constriction.

该方案将研究冠状动脉血管舒缩异常是否可以 通过降低胆固醇的治疗可以逆转。内皮细胞的恢复 功能将由内皮依赖性的返回来表示 扩张为乙酰胆碱并逆转反常收缩。