CRYO FREE 47T ACTIVE SHIELDED ICR SPECTROMETER MAGNET

无冷冻 47T 有源屏蔽 ICR 光谱仪磁铁

• 批准号: 2871170
• 负责人: WEIJUN SHEN
• 金额: $ 8.6万
• 依托单位: CRYOMAGNETICS, INC.
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-05-01 至 1999-10-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2871170
• 关键词: bioengineering /biomedical engineering; biomedical equipment development; cryoscience; cryostat; ion cyclotron resonance spectrometry; magnetic field; nuclear magnetic resonance spectroscopy; superconductivity

This project is aimed at developing a prototype 4.7 tesla cryogen-free high resolution Fourier Transform Mass Spectrometer magnet with an active-shield feature. By using closed cycle refrigeration, system operating cost and the operating complexity will be reduced significantly. The proposed magnet system will be ideal for bio-laboratories to perform spectrum analysis where and when access to liquid cryogens is limited, or where the laboratory space is limited. The Phase I research objective are to demonstrate the feasibility of building a full scale prototype FTMS cryogen-free magnet. To achieve the objectives, Cryomagnetics proposes a technical approach consisting of testing the stability of model coil under persistent mode operation in a cryogen-free environment and integrating it with quench protection circuits to test the complete model. A full scale engineering design of the prototype 4.7T high resolution FTMS magnet will be developed which will be the starting point for Phase II program fabrication of the prototype 4.7T magnets. The new technologies developed in Phase I and II will generate great commercial impact by reducing FTMS system operating cost and increasing flexibility. The successful completion of Phase II of this project will make high mobility; high resolution FTMS magnets available in the market. PROPOSED COMMERCIAL APPLICATION: The increased sensitivity, spectral resolution mobility and reduced the operating cost which the proposed FTMS magnet offer will yield more detailed biological information in a non-invasive manner. The successful completion of this project will help American companies to compete in this fast-growing, $2 billion/annual worldwide market.

该项目旨在开发一种具有主动屏蔽功能的4.7特斯拉无冷冻剂高分辨率傅里叶变换质谱仪磁体原型。 通过采用闭式循环制冷，系统运行成本和操作复杂性将显著降低。 拟议的磁铁系统将是理想的生物实验室进行光谱分析时，液体冷冻剂的访问是有限的，或在实验室空间有限。 第一阶段的研究目标是证明建立一个全尺寸的原型FTMS无致冷剂磁体的可行性。 为了实现这些目标，Cryomagnetics提出了一种技术方法，包括在无低温环境中测试模型线圈在持续模式操作下的稳定性，并将其与失超保护电路集成以测试完整的模型。 将开发原型4.7T高分辨率FTMS磁体的全尺寸工程设计，这将是原型4.7T磁体的第二阶段计划制造的起点。 在第一和第二阶段开发的新技术将通过降低FTMS系统的运营成本和增加灵活性产生巨大的商业影响。 该项目第二阶段的成功完成将使高流动性;高分辨率FTMS磁体在市场上可用。拟定商业应用：所提出的FTMS磁体提供的增加的灵敏度、光谱分辨率移动性和降低的操作成本将以非侵入性方式产生更详细的生物信息。 该项目的成功完成将有助于美国公司在这个快速增长的每年20亿美元的全球市场中竞争。