CRYO-FREE 4.7 ACTIVE-SHEILD ICR SPECTROMETER MAGNET

无冷冻 4.7 有源屏蔽 ICR 光谱仪磁铁

• 批准号: 6211537
• 负责人: WEIJUN SHEN
• 金额: $ 15.23万
• 依托单位: CRYOMAGNETICS, INC.
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-05-01 至 2002-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6211537
• 关键词: bioengineering /biomedical engineering; biomedical equipment development; cryoscience; cryostat; infrared spectrometry; interferometry; ion cyclotron resonance spectrometry; magnetic field; mass spectrometry; superconductivity

This project is aimed at developing a prototype 4.7 Tesla cryogen-free high resolution Fourier Transform Mass Spectrometer magnet with active- shielding. By using close-cycle refrigeration, system operating cost and the operating complexity will be reduced significantly. The proposed magnet system will be ideal for bio-laboratories performing spectrum analysis where and when access to liquid cryogen is limited, or where the laboratory space is limited. The primary Phase II research objective is to build, test and evaluate a full scale 4.7 Tesla FTMS cryogen-free magnet system. To achieve the objective, Cryomagnetics, Inc. proposes a technical approach that consists of testing the stability of NbTi coils in LHe under persistent mode operation to insure each coil's performance, and then assembling coils with high-Tc current leads and quench protection system and testing the complete magnet in cryogen-free environment with the aid of cryocooler. At the end of Phase II research, a full scale 4.7 T, active-shielded FTMS prototype magnet will have been developed and fully tested. This prototype magnet will be the selling point for Phase III program--the commercialization of cryogen-free 4.7 T active-shielded FTMS magnet system. The new technologies developed in Phase I and II will generate great commercial impact by reducing FTMS system operating cost and increasing flexibility. The successful completion of Phase II of this project will make high mobility, high resolution ICR-FTMS magnets available in the market. PROPOSED COMMERCIAL APPLICATIONS: The elimination of the need for liquid cryogens will reduce system down time, improve operator safety, and reduce operating costs in ICR-FTMS bio- research laboratories. Combined with the elimination of stray magnetic fields through the use of active shielding, the proposed system will redefine the already rapidly growing worldwide market for FTMS systems.

本项目旨在开发一种具有主动屏蔽的4.7特斯拉无冷冻剂高分辨率傅里叶变换质谱仪磁体原型。通过采用闭式循环制冷，系统运行成本和操作复杂性将大大降低。拟议的磁铁系统将是理想的生物实验室进行光谱分析时，液体冷冻剂的访问是有限的，或在实验室空间有限。 第二阶段的主要研究目标是建立，测试和评估一个全尺寸的4.7特斯拉FTMS无低温磁体系统。为了实现这一目标，Cryomagnetics，Inc.提出了一种技术途径，即先在液氦中测试NbTi磁体线圈在持久模式下的稳定性，以确保每个线圈的性能，然后将线圈与高Tc电流引线和失超保护系统组装起来，并在无制冷剂环境中借助制冷机对整个磁体进行测试。在第二阶段研究结束时，将开发并全面测试全尺寸4.7 T主动屏蔽FTMS原型磁体。该原型磁体将成为第三阶段计划的卖点-无制冷剂4.7 T主动屏蔽FTMS磁体系统的商业化。在第一和第二阶段开发的新技术将通过降低FTMS系统的运营成本和增加灵活性产生巨大的商业影响。该项目第二阶段的成功完成将使高迁移率，高分辨率的ICR-FTMS磁体在市场上可用。拟议的商业应用：消除对液体冷冻剂的需求将减少系统停机时间，提高操作员安全性，并降低ICR-FTMS生物研究实验室的运营成本。结合通过使用主动屏蔽消除杂散磁场，拟议的系统将重新定义已经迅速增长的FTMS系统全球市场。