CIGAR SMOKING AND PERIODONTAL DISEASE

吸雪茄与牙周病

• 批准号: 2611595
• 负责人: ELIZABETH A KAYE
• 金额: $ 12.17万
• 依托单位: BOSTON UNIVERSITY MEDICAL CAMPUS
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-09-01 至 2002-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2611595
• 关键词: alcoholic beverage consumption; bone density; clinical research; dental plaque; dental radiography; disease /disorder etiology; gingiva; human middle age (35-64); human morbidity; human old age (65+); human subject; longitudinal human study; male; pathologic process; periodontium disorder; questionnaires; smoking; tobacco abuse; tooth loss

DESCRIPTION (Adapted from the Applicant's Abstract): Cigar consumption has seen a significant and rapid rise in the United States in the past three to five years. Very little is known about the influence of cigar smoking on periodontal disease and tooth loss. In contrast, the detrimental effects of another tobacco product, cigarettes, on these oral outcomes are well established and knowledge of cigarette status helps the dentist decide on appropriate therapies for patients who smoke. It is hypothesized that cigar smokers should also be regarded as a high risk groups for periodontal disease. The aims of this proposed 3-year study are: (1) to describe the prevalence of clinical periodontal disease indicators in men who smoke cigars exclusively and compare them to men who never used tobacco products; (2) estimate the loss of alveolar bone mass that is attributable to cigar smoking independently of the rates of tooth loss over a two-year period in cigar smokers and nonsmokers. The subjects are 250 men aged 50 and older who are enrolled in one of three existing cohorts, the Normative Aging Study, The Dental Longitudinal Study, and the Veterans Health Study. All men in each cohort who currently smoke cigars (exclusive of other forms of tobacco use) will be invited to participate (n=125). A group of 125 men who never smoked will be selected, matching on age and study cohort. Each subject will undergo a baseline examination that includes 7 bitewing radiographs; measurements of tooth number, probing pocket depth, plaque, calculus, gingival assessment, clinical attachment loss, decay and restorations; and assessment by questionnaire of alcohol use, medical history, oral hygiene and dental utilization, and dietary intake. Interim changes in alcohol use, oral hygiene and dental utilization will be assessed by mailed questionnaires at 1 year. The examinations and questionnaires will be repeated two years later. Change in alveolar bone mass will be determined from the radiographs by digitized subtraction analysis. Analyses will be performed on baseline data to compare the prevalence of periodontal disease between cigar smokers and nonsmokers. In longitudinal analyses, rates of tooth loss, alveolar bone loss, and changes in clinical attachment loss and probing pocket depth will be compared between cigar smokers and non smokers to estimate the proportion of change in each that is attributable to cigar smoking.

描述（改编自申请人的摘要）： 在过去的三年里， 五年 人们对吸烟的影响知之甚少。 牙周病和牙齿脱落。 相反， 另一种烟草产品，香烟，对这些口腔的结果是好的， 建立和香烟状态的知识有助于牙医决定 对吸烟的患者进行适当的治疗。 据推测，雪茄 吸烟者亦应被视为牙周炎的高危人士。 疾病 这项为期3年的研究的目的是：（1）描述 吸烟男性牙周病临床指标的患病率 雪茄，并将其与从不使用烟草产品的男性进行比较; (2)估计因雪茄引起的牙槽骨质量损失 吸烟与牙齿脱落率无关， 吸烟者和不吸烟者 研究对象为250名50岁及以上的男性 谁参加了现有的三个队列之一，规范老龄化 牙科纵向研究和退伍军人健康研究。 所有 每个队列中目前吸烟的男性（不包括其他形式的 吸烟）将被邀请参加（n=125）。 一个由125名男子组成的小组， 将选择从不吸烟的受试者，年龄和研究队列匹配。 每个 受试者将接受基线检查，包括7次咬翼 X光片;测量牙齿数量，探测袋深度，牙菌斑， 牙石、牙龈评估、临床附着丧失、龋齿和 酒精使用情况、医疗状况、 病史、口腔卫生和牙科使用以及饮食摄入。 临时 将评估酒精使用、口腔卫生和牙科使用的变化 通过邮寄问卷调查1年。 考试和问卷调查 将在两年后重复。 牙槽骨质量的变化将 通过数字化减影分析从射线照片确定。 分析 将对基线数据进行比较， 吸烟者和不吸烟者之间的疾病。 在纵向分析中， 牙齿脱落率、牙槽骨丢失率和临床附着变化 将比较雪茄吸烟者和非吸烟者的损失和探测袋深度 吸烟者估计的比例变化，在每一个可归因于 抽雪茄