NEW BIOCOMPATIBLE TI FOR MAXILLOFACIAL PROSTHESES

描述：这项研究将开发新的生物相容性材料 颌面部假体。目前，纯钛的形态并不是 最适合口腔和颌面部植入物。适用于大面积 颌面种植体的应用，纯钛金属仍不足 力量。另一个问题是控制纯净的表面活性。 天哪。在存在微量杂质的情况下的非化学计量比氧 影响纯钛种植体的长期生物相容性和稳定性。 这项研究将开发新的植入生物材料来克服这些 但保留了纯钛金属的卓越生物兼容性。 第一阶段将演示铸造高强度钛材料以获得更高的体积 强度和化学稳定性，以及一种新的工艺 钛金属表面的稳定化。第二期将扩大 开发更广泛的高强度钛材料。这项工作 将包括材料分析、表面表征和 性能评估和制造优化。文化与文化 将进行临床研究，以验证体外测试和 临床表现研究，以显示这些有益的因素 新型植入物生物材料。 建议的商业应用：不可用

DESCRIPTION: This research will develop new biocompatible materials for maxillofacial prostheses. At present, pure forms of titanium are not optimum for oral and maxillofacial implants. For large-area maxillofacial implant application, pure Ti metals still lack sufficient strength. Another problem is to control the surface activity of pure Ti. Non-stoichiometric oxygen in the presence of trace impurities which affect the long-term biocompatibility and stability of pure Ti implants. This research will develop new implant biomaterials to overcome these problems but retain the superior biocompatibility of pure Ti metals. Phase I will demonstrate cast high-strength Ti materials for higher bulk strength and chemical stability, and a novel process for the stabilization of Ti metal surfaces. Phase II will expand the development into a wider range of high-strength Ti materials. The work will include materials analysis, surface characterization, and performance evaluation and fabrication optimization. Culture and clinical studies will be conducted to verify in-vitro testings and clinical performance studies to show the beneficial factors for these new implant biomaterials. PROPOSED COMMERCIAL APPLICATION: NOT AVAILABLE