INFORMED CONSENT TO DNA BANKING FOR RESEARCH

DNA 银行研究知情同意书

• 批准号: 2889691
• 负责人: Jon F. Merz
• 金额: $ 19.88万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-09-30 至 2001-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2889691
• 关键词: DNA; behavioral /social science research tag; genetic registry /resource /referral center; health care policy; health related legal; health science research; health services research tag; human genetic material tag; human subject; informed consent; interview; questionnaires; tissue resource /registry

DESCRIPTION: The applicants will continue work on a consent form for a DNA bank at the University of Pennsylvania. Patients in the GCRC for other studies are invited to donate to the DNA bank; the investigators will use that population as test subjects for an improved consent process. They will use focus groups and then a "think aloud" protocol (a modified focus group) and prospective jurors as test populations. They will then randomize 2500 subjects, half of whom will use a consent process using vignettes, to see if that technique elicits more informed consent. Subjects will complete a questionnaire about the consent process, assessing their understanding of key issues.

描述：申请人将继续工作的同意书的DNA 宾夕法尼亚大学的银行。GCRC中的其他患者 研究被邀请捐赠给DNA库;研究人员将使用 作为测试对象来改进同意程序 他们将使用焦点小组，然后是一个“大声思考”的协议（一个修改后的协议）。 焦点小组）和潜在陪审员作为测试人群。然后他们将 随机分配2500名受试者，其中一半将使用知情同意程序， 小插曲，看看这种技术是否能获得更多的知情同意。科目 将完成一份关于同意过程的问卷，评估他们的 理解关键问题。

项目成果

The ethics of research on informed consent.

知情同意研究的伦理学。

• DOI: 10.1016/s0197-2456(01)00199-4
• 发表时间: 2002
• 期刊: Controlled clinical trials
• 作者: Merz,JonF

Pilot study: does the white coat influence research participation?

• DOI: 10.2307/3564292
• 发表时间: 2002-07-01
• 期刊: IRB
• 作者: Merz, Jon F;Rebbeck, Timothy R;Meagher, Emma A
• 通讯作者: Meagher, Emma A