LSUMC MINORITY-BASED COMMUNITY CLINICAL ONCOLOGY PROGRAM

LSUMC 基于少数民族的社区临床肿瘤学项目

• 批准号: 6128615
• 负责人: ROBERT W VEITH
• 金额: $ 9.44万
• 依托单位: LSU HEALTH SCIENCES CENTER
• 依托单位国家: 美国
• 财政年份: 1994
• 资助国家: 美国
• 起止时间: 1994-08-12 至 2001-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6128615
• 关键词: behavioral /social science research tag; cancer information system; cancer prevention; cancer rehabilitation /care; clinical research; clinical trials; community health services; cooperative study; data management; early diagnosis; health services research tag; human subject; human therapy evaluation; mass screening; medical outreach /case finding; medical rehabilitation related tag; neoplasm /cancer diagnosis; neoplasm /cancer education; neoplasm /cancer therapy; primary care physician

Our community is in need of improved care for patients with malignant diseases, especially our minority population. Our long-term goals are to bring the advantages of cancer control and state-of-the-art cancer treatment to a much larger number of patients in our target population. In order to enhance the accrual of patients, especially minority patients, we need to dramatically expand our support structure. We have a strong history of a multi-disciplinary effort in cancer care by a large number of health care professionals, which can potentially reduce the morbidity and mortality as well as the cancer incidents in this targeted population. Unfortunately, we have had a dearth of support personnel required to expand our work. This proposal aims to dramatically increase the Data Management personnel and support structure needed to provide ample opportunity to expand our clinical cancer research. Our multi-center approach allows us access to two of the three largest urban areas with the highest concentration of minorities. This is important since minority accrual to NCI cancer research protocols has been so poor. By enrolling more of this underserved population to national trials, it is hoped that the overall care of this population can be improved. This is an ambitious multi-center approach, using a centralized data management system, to recruit and follow-up patients. Epidemiologists at our institution have identified excess mortality compared to the incidence of many cancers. Excess mortality is especially found among the minority population of the state. Efforts are underway within the state to determine the high mortality compared to incidence for these cancers but the main factor appears to be delay in diagnosis. Access to care, per se, is not a factor since Louisiana is unique among states in having a state-wide, state-run system for indigent care. Despite this system, patients do not appear to present for diagnosis in a timely fashion. Factors which could effect patient delay in diagnosis are lack of information about cancer screening. LSU has participated in several cooperative trial groups and has a proven commitment to enrollment of all investigators into one organizational structure with centralized data management, thus eliminating duplication. Streamlining this operation will allow greater access to new populations in the southern part of the state. Increasing enrollments in cancer treatment and control trials should have an enhanced effect in promoting screening and earlier access to care for all the citizens of the state, especially the minority populations.

我们的社区需要改善对恶性肿瘤患者的护理。 疾病，尤其是少数民族。我们的长期目标是 带来癌症控制和最先进癌症治疗的优势， 在我们的目标人群中有更多的患者接受治疗。 为了提高患者，特别是少数民族患者的收益， 我们需要大幅度扩大我们的支持结构。我们有一个强大 历史上的一个多学科的努力，在癌症护理的大量 卫生保健专业人员，这可能会降低发病率， 死亡率和癌症发病率。 不幸的是，我们缺乏所需的支持人员， 扩大我们的工作。该提案旨在大幅增加数据 需要管理人员和支助结构， 扩大我们的临床癌症研究的机会。我们的多中心 这种方式使我们能够进入三个最大的城市地区中的两个， 少数民族的高度集中。这一点很重要，因为少数 NCI癌症研究方案的收益非常低。通过入组 更多的这种服务不足的人口进行国家试验，希望， 对这一群体的总体护理可以得到改善。这是一个雄心勃勃 多中心方法，使用集中式数据管理系统， 招募和随访患者。 我们机构的流行病学家 与许多癌症的发病率相比， 死亡率过高的现象在少数民族人口中尤为明显， 状态目前，该州正在努力确定 死亡率与这些癌症的发病率相比， 似乎是诊断延迟。获得护理本身不是一个因素， 因为路易斯安那州是唯一一个拥有全州范围内，国营 为贫困者提供医疗服务。 尽管有这个系统，病人似乎并不 以便及时诊断。可能影响 患者延误诊断是因为缺乏有关癌症筛查的信息。 路易斯安那州立大学参加了几个合作试验组，并有一个证明 承诺将所有研究者纳入一个组织 数据集中管理，从而消除重复。 精简这一业务将使更多的人能够接触到新的人口 在该州南部。增加癌症登记人数 治疗和对照试验应在促进 筛查和早期获得护理的国家的所有公民， 尤其是少数民族。