LSUHSC Minority Based Community Clinical Oncology

LSUHSC 少数民族社区临床肿瘤学

• 批准号: 6653155
• 负责人: ROBERT W VEITH
• 金额: $ 25.23万
• 依托单位: LSU HEALTH SCIENCES CENTER
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-06-01 至 2009-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6653155
• 关键词: behavioral /social science research tag; cancer information system; cancer prevention; cancer rehabilitation /care; clinical trials; community health services; cooperative study; data management; early diagnosis; health services research tag; human subject; human therapy evaluation; mass screening; medical outreach /case finding; medical rehabilitation related tag; neoplasm /cancer diagnosis; neoplasm /cancer education; neoplasm /cancer therapy; patient oriented research; primary care physician

LSU was a funded Minority-Based Community Clinical Oncology Program (MB CCOP) from 1994 to 2000. Last year's submission received a favorable review but not funding. This submission is an amended application which addresses the points raised in the Summary Statement of last years submission, expands on previous descriptions of our program, and updates our current status. The proposal demonstrates our continued commitment to efforts to cancer control in the minority and under-served populations of southern Louisiana. Cancer mortality is greater than expected based on cancer incidence in Louisiana. This, in part, is due to advanced stage at diagnosis which appears to be greater among underserved and minority population. Access to care is available through a statewide hospital system for indigent populations so the barriers may be more informational than physical or financial. Outreach is what is needed and that is our strength. Although we are successful in treatment efforts, our results in minority enrollment onto cancer prevention studies and the outreach efforts which produces those enrollments will have a greater impact in cancer control. During our first year of the STAR program we enrolled 19% minority women which was roughly ten times that of the national study. This follows a similar success we enjoyed with PCPT where we had four times higher minority enrollment percentage than did the national study. When SELECT opens in September, we are confident the outreach efforts we have established will result in large numbers of African-American men joining the study. We have reversed declines in treatment and cancer control enrollments and propose continued success via the following goals: (1) Continue the collaborative efforts of our capable data management team, (2) Increase participation in STAR and add SELECT, (3) Continue to open only those studies likely to achieve accrual, (4) Increase physician incentives for support of the MB CCOP trials, (5) Carefully weigh expansion opportunities to remain focused on our goal of outreach to minority and under-served populations of Louisiana. The financial support of the National Cancer Institute will assure our continued success.

从 1994 年到 2000 年，路易斯安那州立大学是一个受资助的少数民族社区临床肿瘤学计划 (MB CCOP)。去年的提交获得了好评，但没有获得资助。本提交内容是修订后的申请，解决了去年提交的摘要声明中提出的要点，扩展了我们计划的先前描述，并更新了我们当前的状态。该提案表明了我们对路易斯安那州南部少数族裔和服务不足人群癌症控制努力的持续承诺。根据路易斯安那州的癌症发病率，癌症死亡率高于预期。这在一定程度上是由于诊断已处于晚期，这种情况在服务不足和少数族裔人群中似乎更为严重。贫困人口可以通过全州范围的医院系统获得护理服务，因此障碍可能更多是信息方面的，而不是物质或经济方面的。外展是我们所需要的，也是我们的力量。尽管我们在治疗方面取得了成功，但我们在少数族裔纳入癌症预防研究方面的成果以及促成这些入学的外展工作将对癌症控制产生更大的影响。在 STAR 计划的第一年，我们招募了 19% 的少数族裔女性，大约是全国研究的十倍。在此之前，我们在 PCPT 中取得了类似的成功，我们的少数族裔入学率比全国研究高四倍。当 SELECT 于 9 月开始时，我们相信我们所开展的推广工作将吸引大量非裔美国男性加入这项研究。我们扭转了治疗和癌症控制入组人数下降的趋势，并建议通过以下目标继续取得成功：(1) 继续与我们有能力的数据管理团队合作，(2) 增加 STAR 的参与并添加 SELECT，(3) 继续只开放那些可能实现应计增长的研究，(4) 增加医生对 MB CCOP 试验支持的激励，(5) 仔细权衡扩展机会，继续专注于我们向少数族裔和服务不足人群推广的目标 路易斯安那州。国家癌症研究所的财政支持将确保我们持续取得成功。