ULTRASONIC ELASTICITY IMAGING OF THE BREAST

描述（改编自申请人的摘要）：检查此目的 本项目是开发弹性成像作为一种新的方法， 用于检测癌症和监测复发的医学成像。在这 研究中，通过比较之前记录的超声回波和 在对组织进行小的物理压缩之后。所述比较提供 用于估计局部组织位移的确定 沿着声束的轴的沿着纵向应变。应变成像在此 方法是一种触诊技术，揭示僵硬的变化， 组织具有比手动触诊更高的灵敏度和空间分辨率。 拟议的方法建立在之前四年研究的基础上，有六个 具体目标：1）开发用于乳房成像的鲁棒图像形成算法。 2)与工业界合作，设计用于应变成像的仪器 乳房3)使用Phantomy开发乳房组织约束装置。四、 对人类受试者进行初步临床试验。5)检查 其他弹性参数的诊断潜力。6)评估业绩 为重要的临床诊断问题开发技术， 管理乳腺疾病。

DESCRIPTION (Adapted from Applicant's Abstract): Check ThisThe objective of this project is the development of elasticity imaging as a new approach to medical imaging for detection of cancer and monitoring for recurrence. In this research, images are formed by comparing ultrasonic echoes recorded before and after a small physical compression of the tissue. The comparison provides a determination of local tissue displacement that is used to estimate longitudinal strain along the axis of the sound beam. Strain imaging in this way is a kind of palpation technique that reveals stiffness variations in tissues with higher sensitivity and spatial resolution than manual palpation. The proposed approach, which builds on four years of previous research, has six specific aims: 1) Develop robust image formation algorithms for breast imaging. 2) Work with industry to design instrumentation for strain imaging of the breast. 3) Use phantoms to develop breast-tissue-restraining devices. 4) Conduct preliminary clinical trials on human subjects. 5) Examine the diagnostic potential of other elasticity parameters. 6) Assess the performance of developing techniques for the important clinical problem of diagnosing and managing breast disease.