ULTRASONIC ELASTICITY IMAGING OF THE BREAST

描述(改编自申请者摘要)：勾选此项目标 本项目是弹性成像的发展，作为一种新的方法 用于检测癌症和监测复发的医学成像。在这 研究表明，图像是通过比较之前记录的超声回波和 在对组织进行一次小的物理压缩之后。这种比较提供了一种 用于估计的局部组织移位的确定 沿声束轴线的纵向应变。应变成像在这个 Way是一种触诊技术，它揭示了 组织比人工触诊具有更高的灵敏度和空间分辨率。 拟议中的方法建立在之前四年研究的基础上，有六个 具体目标：1)开发用于乳房成像的稳健成像算法。 2)与工业界合作设计用于应变成像的仪器 胸部。3)利用模特儿开发乳房组织抑制装置。4) 在人类受试者身上进行初步临床试验。5)检查 其他弹性参数的诊断潜力。6)绩效考核 为诊断和诊断的重要临床问题开发技术 管理乳房疾病。

DESCRIPTION (Adapted from Applicant's Abstract): Check ThisThe objective of this project is the development of elasticity imaging as a new approach to medical imaging for detection of cancer and monitoring for recurrence. In this research, images are formed by comparing ultrasonic echoes recorded before and after a small physical compression of the tissue. The comparison provides a determination of local tissue displacement that is used to estimate longitudinal strain along the axis of the sound beam. Strain imaging in this way is a kind of palpation technique that reveals stiffness variations in tissues with higher sensitivity and spatial resolution than manual palpation. The proposed approach, which builds on four years of previous research, has six specific aims: 1) Develop robust image formation algorithms for breast imaging. 2) Work with industry to design instrumentation for strain imaging of the breast. 3) Use phantoms to develop breast-tissue-restraining devices. 4) Conduct preliminary clinical trials on human subjects. 5) Examine the diagnostic potential of other elasticity parameters. 6) Assess the performance of developing techniques for the important clinical problem of diagnosing and managing breast disease.