Causes and consequence of human trait variation

人类性状变异的原因和后果

• 批准号: FL180100072
• 负责人: Prof Peter Visscher
• 金额: $ 238.57万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Australian Laureate Fellowships
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-09-01 至 2024-08-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/FL180100072
• 关键词: Causes; consequence; human; trait; variation

This project aims to exploit the availability of Big Data from the genomics revolution to understand the relationship between the genome, the environment and complex human traits. New statistical methods and user-friendly software tools will be developed and applied to datasets on millions of individuals to generate new knowledge on human life history variation and healthy ageing. This project will position Australia to benefit from rapid advances in genomic technologies, to build and sustain critical capacity in statistical genetics, and better understand the causes and consequence of individual differences in human traits from genetic and environmental factors across the entire human lifespan.

该项目旨在利用基因组学革命中大数据的可用性，以了解基因组，环境和复杂的人类特征之间的关系。将开发新的统计方法和方便用户的软件工具，并将其应用于数百万人的数据集，以产生关于人类生活史变化和健康老龄化的新知识。该项目将使澳大利亚受益于基因组技术的快速发展，建立和维持统计遗传学方面的关键能力，并更好地了解整个人类生命周期中遗传和环境因素导致的人类特征个体差异的原因和后果。