ASSESSING PATIENT PREFERENCES FOR VISUAL ACUITY LOSS
ASSESSING PATIENT PREFERENCES FOR VISUAL ACUITY LOSS
批准号:
2888577
负责人:
ROBERT F NEASE
金额:
$24.06万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
1997
资助国家:
美国
项目状态:
已结题
起止时间:
1997-09-30 至 2000-09-29
关键词:
cataract chorioretinitis clinical research computer data analysis cytomegalovirus retinitis data collection methodology /evaluation diabetic retinopathy eye disorder eye disorder chemotherapy eye disorder diagnosis eye refraction disorder glaucoma health care cost /financing human population study human subject human therapy evaluation interview macular degeneration medical rehabilitation related tag meta analysis outcomes research quality of life questionnaires uveitis vision aid visual perception
中文摘要
(申请人摘要)干预措施所提供的好处
英文摘要
DESCRIPTION:(Applicant's Abstract) The benefit offered by interventions that
prevent or treat visual impairments primarily reflect gains in quality
rather than length of life. The broad objective of the proposed project is
to measure and characterize the impact of a variety of eye diseases on
quality of life. W will measure quality of life by assessing patients'
utilities. Because utilities are quantitative measures of patient
preferences for health states, they offer a means to evaluate the magnitude
of health benefit offered by health interventions. Specifically, formal
methods such as cost-effectiveness analysis rely on utilities to quantify
the effects of interventions on quality of life.
The primary specific aim of the proposed project is to describe the burden
of various eye diseases (and thus the potential benefit of treatment and
prevention) in units of utility. To accomplish this aim, we will assess
utilities, clinical parameters (e.g., visual acuity) and functioning (e.g.,
th National Eye Institute's 25 question Visual Functioning Questionnaire, or
NEI VFQ) in 600 patients, each with one of six target eye diseases
(cataract, diabetic retinopathy, age-related macular degeneration, CMV
retinitis, uveitis and glaucoma), and in 100 patients with no eye disease
other than refractive error. In addition, we will investigate: (1) the
variation in utilities among patients with similarly severe eye disease, (2)
the variation in utilities across patients with different eye diseases,
adjusting for differences in visual acuity and other clinical measures, and
(3) possible predictors for patients' utilities for eye disease, including
disease-related factors (e.g., severity of disease), level of visual
functioning (e.g., the NEI VFQ), and sociodemographic factors (e.g.,
employment).
The data collected in the proposed study will provide an important resource
fo clinicians, policy makers and researchers seeking to evaluate formally
the impacts of eye disease and interventions on quality of life. Rational
clinical and policy decision making requires tradeoffs: are the health
benefits of the intervention under consideration worth the risks and costs?
The proposed project will provide information that is essential to evaluate
the full benefi of treatment of eye disease, and will therefore help
patients and clinicians evaluate the risks and benefits of treatments for
eye disease.
期刊论文(1)
专著(0)
科研奖励(0)
会议论文
The impact of anchor point on utilities for 5 common ophthalmic diseases.
锚点对 5 种常见眼科疾病效用的影响。
DOI:
10.1016/j.ophtha.2007.06.008
发表时间:
2008
期刊:
Ophthalmology
影响因子:
13.7
作者:
[Lee,BryanS, Kymes,StevenM, NeaseJr,RobertF, Sumner,Walton, Siegfried,CarlaJ, Gordon,MaeO]
通讯作者:
Gordon,MaeO
ASSESSING PATIENT PREFERENCES FOR VISUAL ACUITY LOSS
-
批准号:2711218
-
项目类别:
-
资助金额:$24.44万
-
财政年份:1997
-
负责人:ROBERT F NEASE
-
依托单位:
ASSESSING PATIENT PREFERENCES FOR VISUAL ACUITY LOSS
-
批准号:2692192
-
项目类别:
-
资助金额:$1.99万
-
财政年份:1997
-
负责人:ROBERT F NEASE
-
依托单位:
ASSESSING PATIENT PREFERENCES FOR VISUAL ACUITY LOSS
-
批准号:2378128
-
项目类别:
-
资助金额:$20.23万
-
财政年份:1997
-
负责人:ROBERT F NEASE
-
依托单位:
COST-EFFECTIVENESS OF UTILITY ASSESSMENT IN HYPERTENSION
-
批准号:2236137
-
项目类别:
-
资助金额:$6.28万
-
财政年份:1993
-
负责人:ROBERT F NEASE
-
依托单位:
COST-EFFECTIVENESS OF UTILITY ASSESSMENT IN HYPERTENSION
-
批准号:3372999
-
项目类别:
-
资助金额:$17.58万
-
财政年份:1993
-
负责人:ROBERT F NEASE
-
依托单位:
COST-EFFECTIVENESS OF UTILITY ASSESSMENT IN HYPERTENSION
-
批准号:2236136
-
项目类别:
-
资助金额:$8.7万
-
财政年份:1993
-
负责人:ROBERT F NEASE
-
依托单位:
海外基金