GRADUATE TRAINING IN NEUROSCIENCE

本申请要求支持系统和综合生物学的博士前培训，特别强调神经科学的研究生培训。拟议的培训计划包括研究复杂系统的神经科学，如视觉信息的皮质处理、突触传递的分子生物学和神经递质对基因表达的调控。该计划的目标是为学生在神经科学领域的研究生涯做好准备，重点是用多维的方法来解决问题。考虑到这一目标，我们组建了一支能够指导开发、生物化学、细胞电生理学、生物物理学、分子生物学、光子学、心理物理学、皮质功能、计算神经科学和大脑疾病分子遗传学的研究项目的教职员工。由于他们对神经科学的共同兴趣，以及他们致力于为研究生提供教学和实验室培训，这些教职员工聚集在一起实现了这一目标。我们设计了一门课程，将为学生提供广泛的神经科学基础，我们希望这将推动他们的工作，即使他们在神经科学的具体研究可能会发生变化。我们已经准备了一门课程和一系列考试，以检验我们在这方面的进展。我们设有多个机制，以促进不同学系的学生和教职员之间的协作互动，以及监察学生在学习过程中的进度。我们相信，神经科学的博士前培训满足了美国联合国会在创建大脑十年时阐明的重要需求。1989年7月25日颁布的这部法律，是对神经科学研究中许多及时的疾病相关机会的明确认识的结果，并呼吁政府和人民用适当的计划来纪念这个十年。这一神经科学研究生培训计划为这十年做出了重要贡献，通过招募和教育能够进行这一重要努力的年轻科学家，确保其寿命超过2000年。

This application requests support for predoctoral Training in Systems and Integrative Biology with specific emphasis on Graduate Training in Neuroscience. The training program proposed encompasses Neuroscience from the study of such complex systems as the cortical processing of visual information of the molecular biology of synaptic transmission and neurotransmitter regulation of gene expression. The goal of the program is to prepare students for research careers in Neuroscience with an emphasis on a multi-dimensional approach to the problem. With this goal in mind we have assembled a faculty able to direct research projects in development, biochemistry, cellular electrophysiology, biophysics, molecular biology, photonics, psychophysics, cortical function, computational neuroscience, and the molecular genetics of diseases of the brain. These faculty are brought together in this goal by their common interests in Neuroscience and in their commitment to providing both didactic teaching and laboratory training to graduate students. We have designed a curriculum that will provide students with a broad foundation in Neuroscience that we hope will carry them forward in their work even as their specific research in Neuroscience may change. We have prepared a course of study and a series of exams that will test our progress in this endeavor. We have a number of mechanisms in place to promote collaborative interactions between the students and the faculty in different departments and to monitor the progress of student sin their course of study. We believe that this Predoctoral Training in Neuroscience meets an important need articulated by the Joint Congresses of the United States when they created the Decade of the Brain. This Law, enacted on July 25, 1989, resulted from a clear appreciation of the many timely disease related opportunities in Neuroscience research and called upon both the government and the people to observe this decade with appropriate programs. This program in Graduate Training in Neuroscience makes an important contribution to this Decade by ensuring its life beyond the year 2000 through the recruitment and education of young scientists able to carry on this important endeavor.