Graduate Training in Neuroscience

项目概要/摘要 我们建议创建一个灵活的，跨学科的，共同赞助的NIH博士前培训计划， 神经科学（JSPTPN）在研究生的前两年准备优秀的博士生 在基础神经科学研究和相关领域的生产性职业学校。我们提出的方案训练 学生努力了解神经系统的运作，包括教育和研究 有机会识别和改善许多功能障碍和疾病状况，如中风，癫痫， 创伤性脑损伤、神经退行性疾病和成瘾。该计划基于神经科学 研究生组（NGG），一个跨学科的博士课程，包括教师从22个部门在6 宾夕法尼亚大学的学校加上费城附属儿童医院。研究生 宾夕法尼亚大学的生物医学教育是基于这种跨部门的研究生群体， 由生物医学研究生研究办公室（BGS）监督。BGS确保有效的课程开发， 质量控制和统一的录取标准在所有相关的研究生团体，包括NGG。 拟议培训计划的直接管理由一个五人执行委员会完成， 审查政策并挑选学员教师资格是由：1）在相关领域的专业知识， 研究，2）对培训的重大贡献，3）对计划目标的承诺，以及4）校外 资助学员。初级教师接受广泛的指导。学生入学 NGG由全BGS招生委员会审核。随后加入拟议的JSPTPN将 由其执行委员会决定。对每个受训者的支持将涵盖他们在 研究生院培训计划将包括两年的课程加上至少两个实验室轮换。 所有学生将参加关于科学研究负责任行为的年度课程，并将参加 几个新开发的培训内容，侧重于科学方法和统计教学 方法论学生还将通过研讨会，期刊俱乐部，年度务虚会，科学 会议、论文和海报展示以及鼓励互动的社交活动。成功 一个全面的文凭考试的完成标志着独立研究的开始， 论文论文研究是在指导教师的监督下进行的，并由一个 论文委员会和NGG学术评审委员会。论文答辩发生时， 论文指导老师和委员会一致认为工作已经完成。大多数毕业生继续深造 （博士后）培训和追求学术生涯。根据潜在受训人员的数量，我们要求 在今后5年内每年支持12名博士前培训生。

PROJECT SUMMARY/ABSTRACT We propose to create a flexible, interdisciplinary, Jointly Sponsored NIH Predoctoral Training Program in the Neurosciences (JSPTPN) to prepare exceptional predoctoral students in their first two years of graduate school for productive careers in basic neuroscience research and related fields. Our proposed program trains students to work towards understanding the operation of the nervous system, including education and research opportunities to identify and ameliorate many dysfunctional and disease conditions such as stroke, epilepsy, traumatic brain injury, neurodegenerative disorders, and addiction. This program is based in the Neuroscience Graduate Group (NGG), an interdisciplinary PhD program that includes faculty from 22 Departments in 6 Schools of the University of Pennsylvania plus the affiliated Children's Hospital of Philadelphia. Graduate education in biomedical sciences at Penn is based on this kind of interdepartmental Graduate Group and is overseen by the Office of Biomedical Graduate Studies (BGS). BGS ensures effective curricular development, quality control, and uniform admission standards across all relevant Graduate Groups, including the NGG. Direct management of the proposed training program is done by a five-person Executive Committee that sets and reviews policy and selects trainees. Faculty membership is governed by: 1) expertise in a relevant field of study, 2) significant contribution to training, 3) commitment to the goals of the program, and 4) extramural funding to support trainees. Junior faculty receive extensive guidance on mentoring. Admission of students to the NGG is vetted by a BGS-wide admissions committee. Subsequent admission to the proposed JSPTPN will be decided by its Executive Committee. Support for each trainee will encompass their first 21 months in graduate school. The Training Program will consist of two years of coursework plus at least two lab rotations. All students will take a yearly course on the responsible conduct of scientific research and will participate in several newly developed training components that focus on instruction in the scientific method and statistical methodology. Students will also receive training through seminars, journal clubs, annual retreats, scientific meetings, paper and poster presentations, and social events that encourage interactions. Successful completion of a comprehensive Candidacy Examination marks the start of independent research toward the dissertation. Thesis research is conducted under the supervision of a faculty advisor and is monitored by a Thesis Committee and the NGG Academic Review Committee. The dissertation defense takes place when the thesis advisor and committee agree that the work is complete. Most graduates move on for advanced (postdoctoral) training and pursue an academic career. Based on the number of potential trainees, we request support for 12 predoctoral trainees/year for the next 5 years.