AGE-RELATED EYE DISEASE STUDY

年龄相关眼病研究

• 批准号: 6027743
• 负责人: RAYMOND R MARGHERIO
• 金额: $ 32.73万
• 依托单位: OAKLAND UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1990
• 资助国家: 美国
• 起止时间: 1990-03-01 至 2000-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6027743
• 关键词: cataract; clinical trials; diet therapy; dietary trace element; disease /disorder proneness /risk; human middle age (35-64); human subject; human therapy evaluation; macular degeneration; macular drusen; nutrition related tag; pathology; tocopherols; zinc

The purpose of this study, the Aged Related Eye Disease Study (AREDS), is to enroll patients with minor to severe drusen pathology and a) follow the natural progression of macular degeneration; and b) determine if dietary supplements of multivitamins, mineral(s) or multivitamins and minerals delay the progression of the disease. Because patients enrolled will not have optically significant lens opacities, this study will also provide information on development of cataracts in individuals with macular disease. The study will provide new information regarding the progression of macular degeneration and risk factors for cataract formation. Moreover, the effects of dietary supplements in the progression of macular disease and cataract formation will be assessed. The prospective nature of this study, its focus on the progression of drusen pathology, and its evaluation of the effects of dietary supplements make this a unique and much needed study.

这项研究的目的，老年人相关眼病研究（AREDS）， 是招募患有轻微至严重玻璃疣病理的患者，以及a） 跟踪黄斑变性的自然进展;和B）确定 如果多种维生素、矿物质或多种维生素的膳食补充剂， 矿物质可以延缓疾病的发展。 因为患者 入组的受试者不会出现光学显著的透镜混浊，本研究 还将提供有关个人白内障发展的信息 黄斑疾病 该研究将提供有关以下方面的新信息： 黄斑变性的进展和白内障的危险因素 阵 此外，膳食补充剂在 将评估黄斑疾病和白内障形成的进展。 这项研究的前瞻性，其重点是进展， 玻璃疣的病理学，及其饮食影响的评价 补充剂使其成为一项独特且急需的研究。