RURAL MIGRANT DRUG USERS AND THEIR SEXUAL RISKS FOR HIV

农村流动吸毒者及其感染艾滋病毒的性风险

• 批准号: 2897982
• 负责人: H VIRGINIA MCCOY
• 金额: $ 70.2万
• 依托单位: UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-09-01 至 2001-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2897982
• 关键词: AIDS education /prevention; HIV infections; behavior therapy; behavioral /social science research tag; belief; clinical research; crack cocaine; drug abuse; drug abuse prevention; high risk behavior /lifestyle; human subject; human therapy evaluation; mental health counseling; migrant; rural area; sex behavior; sex partner; social support network

DESCRIPTION: (Applicant's Abstract) This five-year collaborative IRPG project is a resubmission in response to Program Announcement 94-054, "Strategies to Reduce HIV Sexual Risk Practices in Drug Users." The research program at the rural South Florida site will focus on developing and implementing sexual risk-reduction interventions targeting rural and migrant crack smokers and their sex partners not currently in drug treatment who are at increased risk of HIV infection/transmission as a consequence of their drug/sexual practices. The research study will be conducted in two phases. The first phase will consist of two sub-phases, 1A and 1B, which together will assess the individual, social, and environmental context of sexual risk behavior and sexual risk reduction, and inform the development of interventions to reduce sexual risk in selected drug-user populations. Phase 1A will elicit in-depth qualitative information about behavioral and normative beliefs, barriers and facilitator, and social influence and network factors related to sexual risk reduction. In Phase 1B, a comprehensive interview instrument about specific risk-reducing sexual behaviors and their antecedents will be developed and administered, guided by data collected in Phase 1A. Additionally, a formalized behavioral context study of sexual risk-reducing behaviors will be conducted with rural and migrant crack smokers and their sexual partners. Based on information gained in Phase 1, theory-driven, empirically informed interventions will be developed and evaluated in a randomized field experimental design for use during Phase 2. The Collier County, FL intervention is a sequenced and additive model in which three types of interventions will be compared: 1) an individual counseling intervention, 2) a Couples counseling intervention, and 3) a Stage-of-change intervention. Intervention strategies will be guided by empirically derived frameworks of behavior change readiness and social influence theories. Randomization will provide the opportunity to measure the additive effects of dyad to individual counseling, individual and couples to group counseling. The three types of interventions will be sequenced in order to measure the separate effects of each intervention type. Although the stated research objectives will be substantially realized by the study design set forth in this proposal for rural South Florida, the value of the proposed initiative will be greatly enhanced by an expected collaboration with two other sites (Houston, Texas and New Orleans, Louisiana) that propose to conduct independent complementary studies for development of sexual risk-reduction interventions within the same theoretical and analytical framework. Each collaborating site will develop unique interventions targeting local populations that will be compared with a standardized control intervention that is uniform across sites. Monitoring of sites (site visits by the executive committee and training by collaborating research associate) will help ensure quality control for intervention integrity, and for data management and analyses.

描述：(申请人摘要) 这个为期五年的合作IRPG项目是对以下问题的重新提交 项目公告94-054，“减少HIV性行为风险的策略” 在南佛罗里达农村地区的研究计划将 重点制定和执行性风险降低干预措施 针对农村和外来吸烟者及其性伴侣不是 目前正在接受药物治疗的人感染艾滋病毒的风险增加 因吸毒/性行为而感染/传播。 研究将分两个阶段进行。第一阶段将 由两个子阶段(1A和1B)组成，这两个子阶段将共同评估 性危险行为的个人、社会和环境背景以及 减少性风险，并通知制定干预措施，以减少 选定吸毒者人群中的性风险。第1A阶段将引发 关于行为和规范信仰的深入定性信息， 障碍和促进者，以及相关的社会影响和网络因素 降低性风险。在1B阶段，一个全面的面谈工具 关于具体的降低风险的性行为及其前置条件将是 根据在第1A阶段收集的数据进行开发和管理。 此外，一项关于降低性行为风险的正式行为背景研究 将对农村和流动人口的吸烟者和他们的 性伴侣。 基于第一阶段获得的信息，理论驱动，经验丰富 干预措施将在随机领域进行开发和评估 第二阶段使用的实验设计。佛罗里达州科利尔县 干预是一种序贯和相加模型，其中三种类型的干预 干预措施将被比较：1)个人咨询干预， 2)夫妻咨询干预；3)改变阶段干预。 干预战略将由经验性的以下框架指导 行为改变准备和社会影响理论。随机化将 提供测量二元体的相加效应的机会 个人咨询、个人和夫妻到团体咨询。这个 将对三种类型的干预措施进行排序，以衡量 每种干预类型的单独效果。 虽然所述研究目标将通过以下方式基本实现 在这项提案中提出的南佛罗里达州农村地区的研究设计 拟议倡议的价值将因预期的 与另外两个站点(德克萨斯州休斯顿和新奥尔良， 路易斯安那州)提议对以下项目进行独立的补充研究 在同一时期内开展减少性风险的干预措施 理论和分析框架。每个合作网站都将开发 针对当地人口的独特干预措施将与 一种标准化的控制干预措施，跨地点统一。 监测工地(执行委员会进行实地考察，并由 合作研究助理)将有助于确保 干预完整性，以及用于数据管理和分析。