Detection and viability of waterborne pathogens using a gut-on-chip

使用芯片肠道检测水生病原体并确定其生存能力

• 批准号: LP170100096
• 负责人: Prof Una Ryan
• 金额: $ 25.03万
• 依托单位: Murdoch University
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Projects
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-12-14 至 2023-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LP170100096
• 关键词: Detection; viability; waterborne; pathogens; using

This project aims to resolve a significant problem for water utilities. Microbial pathogens Cryptosporidium, norovirus and adenovirus are the main public health concern for drinking water in developed nations. Water monitoring is limited by the lack of fast, reliable detection methods and viability assays for these pathogens. This project will use a novel gut-on-a-chip to develop for the first time rapid infectivity assays for Cryptosporidium, norovirus and adenovirus. Significant benefits include improved diagnostics and water disinfection assays, improved water treatment and reduced costs with global impact.

该项目旨在解决供水设施的一个重大问题。隐孢子虫、诺如病毒和腺病毒是发达国家饮用水的主要公共卫生问题。由于缺乏快速、可靠的检测方法和对这些病原体的生存力分析，水监测受到限制。该项目将使用一种新型的肠道芯片首次开发隐孢子虫、诺如病毒和腺病毒的快速感染性检测。显著的好处包括改善诊断和水消毒化验，改善水处理和降低成本，具有全球影响。