GORDON CONFERENCE ON HORMONAL CARCINOGENESIS

本次会议的目的是为那些积极参与定义激素致癌研究前沿的各个学科的权威研究人员提供一个论坛。重要的是，这些研究人员要继续满足监管的目的，讨论在他们各自的领域的最新发展，分析当前研究的意义，讨论新的策略，未解决的问题，批判性地评估当前的理论，并根据需要开发新的理论和方法。1999年的会议将集中讨论作为敏感亚群的分子决定因素，对经尿道介导的癌症至关重要的分子和生物学机制。它将讨论如何利用基本知识制定预防和治疗战略以及环境激素对肿瘤敏感组织的影响。会议将研究与乳腺癌、前列腺癌、子宫内膜癌和垂体癌有关的上述问题。重要的是，它将专注于该领域的两个快速发展的前沿。第一个涉及类固醇激素受体及其结合伙伴（共激活剂和抑制剂）在激素致癌作用的早期步骤中所起的作用，第二个涉及激素对血管生成的影响会议是主要的正在进行的会议，通过汇集专注于激素致癌作用但具有不同方法和观点的科学家，以全面综合的方式讨论激素致癌作用。这种方法有助于激发创造性和创新性的研究策略，这是根除经尿道介导的癌症所必需的。

The aim of this conference is to provide a forum for authoritative investigators who are actively involved in the various disciplines which define the leading edges of research in hormonal carcinogenesis. It is important for such investigators to continue to meet regulatory for the purpose of discussing the latest developments in their individual fields, to analyze the significance of current research, to discuss new tactics for unresolved problems, to critically evaluate current theories, and to develop new theories and approaches as needed. The 1999 conference will focus on the molecular and biological mechanism that are critical to hormonally-mediated cancers as the molecular determinants of sensitive subpopulations. It will address the use of fundamental knowledge in the development of prevention and treatment strategies and the impact of environmental hormones on cancers of hormone-sensitive tissues. The conference will examine the above issues in relation to breast, prostate, endometrial and pituitary cancer. Importantly, it will focus on two fast-moving fronts of the field. The first relates to the role played by steroid hormone receptors and their binding partners, (co-activators and repressors) in the early steps of hormonal carcinogenesis, the second concerns the effects of hormones on angiogenesis The conference is the major ongoing meeting that discusses hormonal carcinogenesis in a comprehensive integrated manner by bringing together scientists who focus on hormonal carcinogenesis but have differing approaches and perspectives. This approach helps stimulate creative and innovative research strategies necessary for the eradication of hormonally-mediated cancers.