GORDON CONFERENCE ON HORMONAL CARCINOGENESIS

本次会议的目的是为积极参与各种学科的权威研究者提供一个论坛，这些学科定义了激素致癌研究的前沿。对于这些研究者来说，为了讨论各自领域的最新发展，分析当前研究的意义，讨论解决未解决问题的新策略，批判性地评估当前理论，并根据需要发展新的理论和方法，继续满足监管要求是很重要的。1999年的会议将集中讨论对激素介导的癌症至关重要的分子和生物学机制，作为敏感亚群的分子决定因素。它将讨论在预防和治疗策略的发展中使用基础知识以及环境激素对激素敏感组织癌症的影响。会议将探讨上述与乳腺癌、前列腺癌、子宫内膜癌和脑垂体癌有关的问题。重要的是，它将关注该领域两个快速发展的前沿。第一个会议涉及类固醇激素受体及其结合伙伴（共激活物和阻遏物）在激素致癌的早期阶段所起的作用，第二个会议涉及激素对血管生成的影响。该会议是正在进行的主要会议，通过将关注激素致癌但有不同方法和观点的科学家聚集在一起，以综合的方式讨论激素致癌。这种方法有助于激发根除激素介导的癌症所必需的创造性和创新性研究策略。

The aim of this conference is to provide a forum for authoritative investigators who are actively involved in the various disciplines which define the leading edges of research in hormonal carcinogenesis. It is important for such investigators to continue to meet regulatory for the purpose of discussing the latest developments in their individual fields, to analyze the significance of current research, to discuss new tactics for unresolved problems, to critically evaluate current theories, and to develop new theories and approaches as needed. The 1999 conference will focus on the molecular and biological mechanism that are critical to hormonally-mediated cancers as the molecular determinants of sensitive subpopulations. It will address the use of fundamental knowledge in the development of prevention and treatment strategies and the impact of environmental hormones on cancers of hormone-sensitive tissues. The conference will examine the above issues in relation to breast, prostate, endometrial and pituitary cancer. Importantly, it will focus on two fast-moving fronts of the field. The first relates to the role played by steroid hormone receptors and their binding partners, (co-activators and repressors) in the early steps of hormonal carcinogenesis, the second concerns the effects of hormones on angiogenesis The conference is the major ongoing meeting that discusses hormonal carcinogenesis in a comprehensive integrated manner by bringing together scientists who focus on hormonal carcinogenesis but have differing approaches and perspectives. This approach helps stimulate creative and innovative research strategies necessary for the eradication of hormonally-mediated cancers.