Administrative Core

行政核心

基本信息

  • 批准号:
    8054350
  • 负责人:
  • 金额:
    $ 58.96万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2010
  • 资助国家:
    美国
  • 起止时间:
    2010-04-01 至 2013-03-31
  • 项目状态:
    已结题

项目摘要

Introduction Section 6 describes in detail the tasks of the Administrative Core, the plan to carry out these tasks, and metrics used to evaluate the success of the implemented plans. Also described are membership requirements and procedures for the addition or removal of a member, changes in the structure of the CEG that have taken place, including changes in investigator membership, replacement of Research Cores with Focus Groups, and changes in Facilities Cores, which are more specifically detailed in Section 7 (page 667). Detailed implementation of the Career Development Program will be discussed in Section 4 (page 624). Report of the Pilot Projects Program and description of changes instituted in the program are detailed in Section 8, page 754. Discontinuation of the Outreach portion of the CEG is described below. The overarching objectives of the Center for Environmental Genetics are to improve human health through the integration of basic, genetic, clinical and epidemiological research into clinical practice and public health initiatives. Implementation of these objectives thus constitutes the primary objective of the Administrative Core, which will effectively manage the Center so that these goals can be achieved, creating a neighborhood of residents and facilities that will have an impact on Fig. 1 The Administrative Core will do this not only by overseeing the organizational, budgeting and reporting aspects of the grant, but also, and most importantly, by providing the leadership for the scientific and programmatic activities of the Center as a whole. The Director (Ho), Deputy Director (Puga) and Associate Directors (Lanphear and Nebert) have the responsibility for overall coordination and oversight of Center activities. They provide both scientific leadership and fiscal management for the Center. To carry out these responsibilities,they are assisted by the Internal Advisory Committee (IAC) composed of Focus Group Point Investigators (see Fig. 3 below), Facilities Cores Heads (Fig 1 with *), chosen CEG members, and other University faculty or staff who provide links with allied programs within the University. The Directors and chosen members of the IAC comprise a subcommittee which will be referred as the Executive Committee. It meets on a monthly basis and will assist the directors to oversee the day to day running of the CEG. The advise base is broaden by the inclusion of a Elite Council of UC/CCHMC Experts, comprised of a distinguished panel of UC/CCHMC research and administrative experts (Bishop, Broderick, Khurana-Hershey, and Stambrook), and an External Advisory Committee (EAC), made-up of a distinguished group of outstanding non-UC scientists who provide a strong advisory role focused on human genetics and environmental health as well as substantial experience in administration of large multidisciplinary programs. The Program Manager assists with the day-to-day management of the Center, fiscal monitoring, reporting, organization of group meetings, record keeping, and organization and planning Center activities, workshops and symposia. The Program Manager is assisted by a part-time (30% effort) Grant Administrator (also referred to as Financial Administrator) who oversees all grant related fiscal and compliance issues related to Center activities within and outside the University. The Program Manager is in charge of the semi-annual production of the CEG's Interface newsletter and the routine update of the CEG Website content, under the oversight of the Associate Director, Dr. Daniel Nebert. The Core provides administrative support for the Career Development Program (CDP) headed by Drs. Grace LeMasters and Daniel Woo (see Section 4, page 624) and the Pilot Project Program (PPP) coordinated by the Associate Director of the PPP, Dr. Daniel Nebert, and the Associate Director of Integrative Health, Dr. Bruce Lanphear. Three Facilities and Services (F&S) Cores have been proposed in this resubmission and they all report back to and will be evaluated on performance by the Administrative Core, with informal and formal input and advice from the Executive Committee, the Elite Council of the IAC and the EAC, which meet at different frequencies (detailed below) . The three F&S Cores are the Integrative Technologies Support Core (ITS, Section 7.1, page 667), the Integrative Health Services Core (Section 7.1, page 694) and the Bioinformatics Core (Section 7.3, page 721). Center research is supported by the F&A cores and the PPP awards, as well as training and educational enhancement programs organized by the Administrative Core. Career development, a high priority of the CEG, will be led by seasoned CEG investigators, with a separate budget but support from the Administrative Core. The key role played by the PPP, which is to promote high gain-high reward projects and align award mechanisms to CEG missions, has a separate budget and leadership oversight, but will also be supported by the Administrative Core.
介绍 第6节详细描述了行政核心的任务,执行这些任务的计划和指标 用于评估实施计划的成功。还描述了会员要求和 增加或去除会员的程序,CEG的结构发生了变化 位置,包括调查员成员的变化,用焦点小组替换研究核心以及 设施内核的变化,第7节(第667页)中更具体地详细介绍了。详细的 职业发展计划的实施将在第4节(第624页)中讨论。报告 该计划中提出的更改的试点项目计划和描述在第8节中详细介绍 754。下面介绍了CEG外展部分的中断。 环境遗传学中心的总体目标是改善人类健康 通过将基本,遗传,临床和流行病学研究整合到临床实践中 和公共卫生计划。因此,这些目标的实施构成了 行政核心将有效地管理中心,以便可以实现这些目标,创建一个 居民和设施的邻里将对图1产生影响 行政核心不仅可以通过监督组织,预算和 报告赠款的各个方面,也是最重要的是,通过为 整个中心的科学和程序化活动。 董事(HO),副主任(PUGA)和副董事(Lanphear和Nebert)负责 用于整体协调和监督中心活动。他们提供科学领导和财政 中心的管理。 为了履行这些责任,他们由内部咨询委员会(IAC)协助 焦点小组研究员(见下图3),设施核心(图1带 *),选定的CEG 成员以及其他大学教职员工,他们与大学内的盟军计划提供链接。这 IAC的董事和选择的成员组成了一个小组委员会,该小组委员会将被称为执行官 委员会。它每月开会,并将协助董事监督 CEG日常运行。通过包括一个精英理事会来扩大建议基础 UC/CCHMC专家,由杰出的UC/CCHMC研究和行政专家组成 (Bishop,Broderick,Khurana-Hershey和Stambrook),以及外部咨询委员会(EAC), 由一组杰出的非联盟科学家组成,他们提供了强大的咨询角色 关于人类遗传学和环境健康以及在大型管理方面的丰富经验 多学科计划。计划经理协助该中心的日常管理, 财政监控,报告,小组会议组织,记录保存以及组织和计划 中心活动,研讨会和研讨会。计划经理的兼职协助(30%的努力) 赠款管理员(也称为财务管理员),负责所有相关的财政和 合规性问题与大学内外的中心活动有关。计划经理在 CEG界面通讯的半年度生产和CEG的常规更新的收费 网站内容,在副主任丹尼尔·内伯特(Daniel Nebert)博士的监督下。 核心为由DRS领导的职业发展计划(CDP)提供了行政支持。优雅 Lemasters和Daniel Woo(请参阅第4节,第624页)和试点项目计划(PPP)协调 PPP的副主任Daniel Nebert博士和综合健康副主任,博士 布鲁斯·兰菲尔(Bruce Lanphear)。在此重新提交和 他们都向行政核心,非正式和 执行委员会,IAC和EAC的精英理事会的正式意见和建议, 以不同的频率(下面详细说明)。这三个F&S核心是综合技术支持 核心(第7.1节,第667页),综合保健服务核心(第7.1节,第694页)和 生物信息学核心(第721页,第721页)。中心研究得到了F&A核心和PPP的支持 由行政核心组织的奖项以及培训和教育增强计划。 职业发展是CEG的重点,将由经验丰富的CEG调查人员领导,并单独 预算,但支持行政核心。 PPP扮演的关键角色是为了提升高 获得最高的奖励项目和与CEG任务的奖励机制相结合,有单独的预算,并且 领导监督,但也将得到行政核心的支持。

项目成果

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Shuk-Mei Ho其他文献

Shuk-Mei Ho的其他文献

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{{ truncateString('Shuk-Mei Ho', 18)}}的其他基金

BLRD Research Career Scientist Award Application
BLRD 研究职业科学家奖申请
  • 批准号:
    10589966
  • 财政年份:
    2022
  • 资助金额:
    $ 58.96万
  • 项目类别:
RNA modifications by paternal exposure to arsenic and intergenerational effects on sperm quality
父亲接触砷导致的 RNA 修饰以及对精子质量的代际影响
  • 批准号:
    10615715
  • 财政年份:
    2022
  • 资助金额:
    $ 58.96万
  • 项目类别:
RNA modifications by paternal exposure to arsenic and intergenerational effects on sperm quality
父亲接触砷导致的 RNA 修饰以及对精子质量的代际影响
  • 批准号:
    10391233
  • 财政年份:
    2022
  • 资助金额:
    $ 58.96万
  • 项目类别:
Metal-induced cell-level changes in prostate epithelium and cancer risk
金属诱导的前列腺上皮细胞水平变化和癌症风险
  • 批准号:
    10382227
  • 财政年份:
    2021
  • 资助金额:
    $ 58.96万
  • 项目类别:
Metal-induced cell-level changes in prostate epithelium and cancer risk
金属诱导的前列腺上皮细胞水平变化和癌症风险
  • 批准号:
    10664831
  • 财政年份:
    2021
  • 资助金额:
    $ 58.96万
  • 项目类别:
Effects of Arsenic on Human Prostate Stem Cells and Prostate Cancer Risk
砷对人类前列腺干细胞和前列腺癌风险的影响
  • 批准号:
    8535765
  • 财政年份:
    2012
  • 资助金额:
    $ 58.96万
  • 项目类别:
Effects of Arsenic on Human Prostate Stem Cells and Prostate Cancer Risk
砷对人类前列腺干细胞和前列腺癌风险的影响
  • 批准号:
    8390359
  • 财政年份:
    2012
  • 资助金额:
    $ 58.96万
  • 项目类别:
Effects of Arsenic on Human Prostate Stem Cells and Prostate Cancer Risk
砷对人类前列腺干细胞和前列腺癌风险的影响
  • 批准号:
    9058540
  • 财政年份:
    2012
  • 资助金额:
    $ 58.96万
  • 项目类别:
Effects of Arsenic on Human Prostate Stem Cells and Prostate Cancer Risk
砷对人类前列腺干细胞和前列腺癌风险的影响
  • 批准号:
    8664850
  • 财政年份:
    2012
  • 资助金额:
    $ 58.96万
  • 项目类别:
G-protein coupled receptor-30(GPR30):a putative new therapeutic target for PCa
G蛋白偶联受体30(GPR30):前列腺癌的假定新治疗靶点
  • 批准号:
    8044909
  • 财政年份:
    2011
  • 资助金额:
    $ 58.96万
  • 项目类别:

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  • 批准号:
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