FASEB RESEARCH CONFERENCE--GLUCOSE TRANSPORTER BIOLOGY

会议将于1999年7月17日至22日在科罗拉多州的斯诺马斯村举行。这将是专门讨论葡萄糖转运问题的第四次国际会议。这次会议的目的是聚集一组国际专家，在几个组织层面上讨论葡萄糖运输的各个方面：从分子和细胞到机体葡萄糖动态平衡及其在糖尿病等疾病中的破坏。会议将限制为150名与会者，他们的临床或基础科学背景是根据他们的专业知识和兴趣来选择的。将有八个主要的科学会议，每个会议有4-5次受邀演讲，大约30分钟(20+10讨论)，然后是40分钟的时间，在那里将提出选定的摘要和/或最新数据。在每一次主要会议结束时，还将有20分钟的一般性讨论。会议期间将有一个海报会议，并将有2个海报讨论会议。这将使初级参与者有机会介绍他们的数据并与该领域的专家讨论，如上所述，其中一些将被选作口头介绍。将讨论的具体主题包括：1)葡萄糖转运蛋白的结构/功能，2)谷氨酸与细胞蛋白的相互作用和转运蛋白活性的调节，3)应用于谷氨酸转运蛋白的新方法，4)葡萄糖转运蛋白的合成和降解，5)谷氨酸转运蛋白与病理生理学，6)哺乳动物、蠕虫和酵母中的新谷氨酸转运蛋白，7)转运蛋白激活的信号通路，8)葡萄糖转运蛋白囊泡的运输。这些领域中的争议、不确定性和共识的主题将在充分的讨论时间内进行定义和讨论。这次会议将为对葡萄糖感兴趣的基础科学家和相关的转运蛋白生物学/生物化学/细胞生物学与对这些分子在各种代谢紊乱中的可能作用感兴趣的临床医生之间的互动提供一个独特的机会。正如以前所有会议所证明的那样，互动环境将促进与会者之间的合作研究努力，并有助于确定和制定未来葡萄糖转运蛋白研究的目标。

The conference will take place on July 17-22, 1999 in Snowmass Village, Colorado. This will be the fourth international meeting devoted specifically to the subject of glucose transport. The aim of the conference is to bring together a group of international experts to discuss various aspects of glucose transport, at several organizational levels: from molecular and cellular to organismal glucose homeostasis and its disruption in diseases such as diabetes mellitus. The conference will be limited to 150 participants with clinical or basic science backgrounds chosen on the basis of their expertise and interests. There will be eight major scientific sessions, each with 4-5 invited talks of ca. 30 minutes (20 + 10 discussion) followed by a 40 minute period where selected abstracts and/or late breaking data will be presented. At the end of each major session, there will be an additional 20 minutes of general discussion. There will be a poster session that will be up for the duration of the meeting, and there will be 2 Poster Discussion sessions. These will allow junior participants the opportunity to present and discuss their data with experts in the field, and as noted above, some of these will be chosen for oral presentation. The specific topics to be discussed include: 1) Structure/function of glucose transporters, 2) Interaction of GLUTs with cellular proteins and transport activity modulation, 3) New methodology applied to GLUTs, 4) Glucose transporter synthesis and degradation, 5) GLUTs and pathophysiology, 6) New GLUTs in mammals, worms and yeast, 7) Signaling pathways to transporter activation, 8) GLUT vesicular trafficking. The topics of controversy, uncertainty, and agreement within each of these areas will be defined and discussed in the ample discussion periods. The conference will provide a unique opportunity for interaction between basic scientists interested in glucose and related transporter biology/biochemistry/cell biology with clinicians interested in the possible role of these molecules in various metabolic disorders. As proven the case in all previous meetings, the interactive environment will stimulate collaborative research efforts among participants and help to identify and set future goals for research on glucose transporters.