IMMUNOREGULATION IN ALLERGIC DISEASE

过敏性疾病中的免疫调节

• 批准号: 3105090
• 负责人: Lanny J. Rosenwasser
• 金额: $ 27.92万
• 依托单位: NATIONAL JEWISH HEALTH
• 依托单位国家: 美国
• 财政年份: 1987
• 资助国家: 美国
• 起止时间: 1987-09-01 至 1993-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3105090
• 关键词: asthma; human subject; immunoregulation

The main theme of this asthma and allergic disease center application is focussed on immunoregulation and interaction between cells participating in immunologic and/or inflammatory responses. Most of the investigators involved in this work have a background well founded in immunology, have developed and/or are using in vitro models to study immunologic reactions, and are applying the new information to patients with allergic and hypersensitivity diseases. An example of how we are approaching this problem is presented in the first project in which the effect of immunotherapy in cat-induced asthmatics is being investigated. In this project, several facets of immune function as well as the clinical benefit derived from immunotherapy is being evaluated.

本次哮喘和过敏性疾病中心申请的主题是 侧重于免疫调节和参与的细胞之间的相互作用 免疫和/或炎症反应。大多数调查人员 参与这项工作有很好的免疫学背景，有 开发和/或正在使用体外模型来研究免疫反应， 并将新信息应用于患有过敏症和 过敏症。这是我们如何处理这一问题的一个例子 在第一个项目中提出了问题，在该项目中 对CAT诱导的哮喘患者的免疫治疗正在进行研究。在这 方案、免疫功能的几个方面以及临床益处 来自免疫疗法的药物正在评估中。