ERYTHROCYTE SENESCENCE

红细胞衰老

• 批准号: 3120244
• 负责人: GEORGE LESLIE DALE
• 金额: $ 8.56万
• 依托单位: UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR
• 依托单位国家: 美国
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-01-10 至 1991-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3120244
• 关键词: adenine nucleotides; affinity chromatography; aminoacid metabolism; antibody; antioxidants; avidin; biotin; cell senescence; cell sorting; chickens; erythrocytes; glycolysis; laboratory rabbit; membrane proteins; pentose phosphate shunt

This project is designed to study the short- and long-term impact of alcohol warning labels among Hispanic adults. Specifically, the study proposed here will (a) measure for five years the level of awareness of the existence of alcohol warning labels; (b) identify the impact of the alcohol warning labels in terms of changes in self-reported drinking behavior; (c) measure the reactions of Hispanic adults to the messages in terms of their perceived usefulness and credibility, their effect on motivating the individual to find more information about the effects of alcohol intake as well as the beliefs (knowledge) the respondents have regarding the effects of drinking alcoholic beverages. This study will target Hispanics (primarily Mexican- and Central- Americans) who in recent studies have shown high prevalence rates and the behavioral and health effects of excessive alcohol consumption (high proportion of homicide victims with alcohol in their blood; chronic liver disease as a primary cause of death for males; high proportion of drunk driving arrests). The study will follow a cohort of approximately 500 adult Hispanics for five years (first interviewed during the Summer of 1989). In addition, cross-sectional random samples of 2,000 adult Hispanics will be interviewed every year for five years. The differential effect of gender, age, and acculturation level of the respondents will be analyzed for all of the data collected.

该项目旨在研究短期和长期影响 西班牙裔成年人中的酒精警告标签。 具体地说， 本报告建议的研究将（a）在五年内衡量 了解酒精警告标签的存在;（B） 确定酒精警告标签的影响， 自我报告饮酒行为的变化;（c）测量 西班牙裔成年人对这些信息的反应， 感知的有用性和可信度，它们对激励的影响 个人找到更多的信息， 酒精摄入量以及受访者的信仰（知识） 关于饮酒的影响。 这 这项研究将针对西班牙裔（主要是墨西哥人和中部人）， 最近的研究显示， 以及过量饮酒对行为和健康的影响 酒精消费（酒精中毒的凶杀案受害者比例很高， 他们的血液;慢性肝病是死亡的主要原因 男性;酒后驾车被捕的比例很高）。 研究 将跟踪大约500名西班牙裔成年人的队列， 五年（1989年夏天首次采访）。 在 此外，2,000名西班牙裔成年人的横断面随机样本 将在五年内每年接受采访 差动 受访者的性别、年龄和文化适应程度的影响 将对收集的所有数据进行分析。