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ERYTHROCYTE SENESCENCE

红细胞衰老

基本信息

批准号：
3120246
负责人：
GEORGE LESLIE DALE
金额：
$ 2.74万
依托单位：
UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR
依托单位国家：
美国
项目类别：
财政年份：
1989
资助国家：
美国
起止时间：
1989-01-10 至 1991-12-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/3120246
关键词：
adenine nucleotides affinity chromatography aminoacid metabolism antibody antioxidants avidin biotin cell age cell sorting chickens erythrocytes glycolysis laboratory rabbit membrane proteins

项目摘要

This project is designed to study the short- and long-term impact of alcohol warning labels among Hispanic adults. Specifically, the study proposed here will (a) measure for five years the level of awareness of the existence of alcohol warning labels; (b) identify the impact of the alcohol warning labels in terms of changes in self-reported drinking behavior; (c) measure the reactions of Hispanic adults to the messages in terms of their perceived usefulness and credibility, their effect on motivating the individual to find more information about the effects of alcohol intake as well as the beliefs (knowledge) the respondents have regarding the effects of drinking alcoholic beverages. This study will target Hispanics (primarily Mexican- and Central- Americans) who in recent studies have shown high prevalence rates and the behavioral and health effects of excessive alcohol consumption (high proportion of homicide victims with alcohol in their blood; chronic liver disease as a primary cause of death for males; high proportion of drunk driving arrests). The study will follow a cohort of approximately 500 adult Hispanics for five years (first interviewed during the Summer of 1989). In addition, cross-sectional random samples of 2,000 adult Hispanics will be interviewed every year for five years. The differential effect of gender, age, and acculturation level of the respondents will be analyzed for all of the data collected.

该项目旨在研究短期和长期影响，西班牙裔成年人中的酒精警告标签。具体地说，本报告建议的研究将（a）在五年内衡量对酒精警告标签存在的认识;（B）确定酒精警告标签的影响，自我报告饮酒行为的变化;（c）测量西班牙裔成年人对这些信息的反应，感知的有用性和可信度，它们对激励的影响个人找到更多的信息，酒精摄入量以及受访者的信仰（知识）关于饮酒的影响。这这项研究将针对西班牙裔（主要是墨西哥人和中部人），最近的研究显示，以及过量饮酒对行为和健康的影响酒精消费（酒精中毒的凶杀案受害者比例很高，他们的血液;慢性肝病是死亡的主要原因男性;酒后驾车被捕的比例很高）。研究将跟踪大约500名西班牙裔成年人的队列，五年（1989年夏天首次采访）。在此外，2,000名西班牙裔成年人的横断面随机样本将在五年内每年接受采访差动受访者的性别、年龄和文化适应程度的影响将对收集的所有数据进行分析。