Wheat Genomics for Sustainable Agriculture

可持续农业的小麦基因组学

• 批准号: BB/J00328X/1
• 负责人: Paul Kersey
• 金额: $ 60.02万
• 依托单位: European Bioinformatics Institute
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2012
• 资助国家: 英国
• 起止时间: 2012 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FJ00328X%2F1
• 关键词: Wheat; Genomics; Sustainable; Agriculture

Securing food supply on a global scale requires solutions to a complex set of unprecedented problems, including rising demand due to major population increases and social mobility, global climate change, rising energy costs and land, water and nutrient limitations. Finding and implementing these solutions is a top priority for governments and scientists worldwide, and has been articulated as a key BBSRC strategic objective. Opportunities for plant science to contribute to global food security include increasing the yield and quality of crops, combatting diseases, enabling maximal crop productivity in sub-optimal growth conditions, and increasing maximal yield potential. Utilising non- food components of food crops, such as cell wall material and waste products of food production to produce energy and industrial feedstocks, has a major role in reaching sustainability and maximising overall yield of renewable resources from limited land and soils. Grass crops are essential for human existence by directly or indirectly serving as the primary source of human nutrition. Wheat, rice and coarse grains such as maize are the most important crops for human food production, therefore increasing grain production sustainably is a critically important strategic and scientific objective. Wheat is the main arable crop in the UK, planted on 60% of arable land, with an annual farm gate value of ~£2.5b and a processed product value of approximately £150bn. Yield increases in wheat are slowing compared to past gains achieved primarily through improved agronomy and also in relation to other grain crops, notably maize. Genetic and transgenic improvement of wheat is therefore a very high priority in the UK and world- wide, and large international programmes for wheat genetic improvement are underway. A high quality genomics sequence provides a complete, accurate and durable record of genes, predicted proteins and other genomic elements that today are a fundamental foundation for nearly all areas of biological research. This proposal describes a UK component of an international coordinated wheat genome sequencing project that will make decisive and innovative contributions to sequencing the wheat genome and supporting crop improvement through genomics.

确保全球范围的粮食供应需要解决一系列前所未有的复杂问题，包括人口大幅增加和社会流动性导致的需求增加、全球气候变化、能源成本上升以及土地、水和营养有限。寻找和实施这些解决方案是世界各国政府和科学家的首要任务，也是BBSRC的关键战略目标。植物科学为全球粮食安全做出贡献的机会包括提高作物的产量和质量，防治疾病，在次优生长条件下实现最大作物生产力，以及提高最大产量潜力。利用粮食作物的非粮食成分，如细胞壁材料和粮食生产的废物来生产能源和工业原料，在实现可持续性和从有限的土地和土壤中最大限度地提高可再生资源的总产量方面发挥着重要作用。禾本科作物直接或间接地作为人类营养的主要来源，对人类的生存至关重要。小麦、水稻和玉米等粗粮是人类最重要的粮食生产作物，因此可持续地增加粮食产量是一个至关重要的战略和科学目标。小麦是英国主要的可耕地作物，种植在60%的耕地上，每年的农场价值约为25亿英镑，加工产品价值约为1500亿英镑。与过去主要通过改进农艺取得的收益相比，小麦的产量增长正在放缓，与其他粮食作物，特别是玉米相比，小麦的产量增长也在放缓。因此，小麦的遗传和转基因改良在英国和世界范围内都是非常优先的，并且正在进行小麦遗传改良的大型国际计划。高质量的基因组学序列提供了基因、预测蛋白质和其他基因组元素的完整、准确和持久的记录，这些基因组元素是当今几乎所有生物研究领域的基础。该提案描述了国际协调小麦基因组测序项目的英国组成部分，该项目将为小麦基因组测序和通过基因组学支持作物改良做出决定性和创新性贡献。

项目成果

De novo transcriptome assembly and analyses of gene expression during photomorphogenesis in diploid wheat Triticum monococcum.

• DOI: 10.1371/journal.pone.0096855
• 发表时间: 2014
• 期刊: PloS one
• 影响因子: 3.7
• 作者: Fox SE;Geniza M;Hanumappa M;Naithani S;Sullivan C;Preece J;Tiwari VK;Elser J;Leonard JM;Sage A;Gresham C;Kerhornou A;Bolser D;McCarthy F;Kersey P;Lazo GR;Jaiswal P
• 通讯作者: Jaiswal P

An improved assembly and annotation of the allohexaploid wheat genome identifies complete families of agronomic genes and provides genomic evidence for chromosomal translocations

• DOI: 10.1101/080796
• 发表时间: 2016-10
• 期刊: Genome Research
• 影响因子: 7
• 作者: Bernardo J. Clavijo;Luca Venturini;Christian Schudoma;G. G. Accinelli-G.;G. Kaithakottil;Jonathan Wright;P. Borrill;George Kettleborough;D. Heavens;Helen Chapman;J. Lipscombe;Tom Barker;Fu-Hao Lu;N. McKenzie;Dina Raats;R. Ramirez-Gonzalez;Aurore Coince;Ned Peel;Lawrence Percival-Alwyn;Owen Duncan;Josua Trösch;Guotai Yu;D. Bolser;Guy Namaati;A. Kerhornou;M. Spannagl;H. Gundlach;G. Haberer;Robert P. Davey;Christine Fosker;F. Palma;A. Phillips;A. Millar;P. Kersey;C. Uauy;K. Krasileva;D. Swarbreck;M. Bevan;M. Clark

Ensembl Genomes 2018: an integrated omics infrastructure for non-vertebrate species.

• DOI: 10.1093/nar/gkx1011
• 发表时间: 2018-01-04
• 期刊: Nucleic acids research
• 影响因子: 14.9
• 作者: Kersey PJ;Allen JE;Allot A;Barba M;Boddu S;Bolt BJ;Carvalho-Silva D;Christensen M;Davis P;Grabmueller C;Kumar N;Liu Z;Maurel T;Moore B;McDowall MD;Maheswari U;Naamati G;Newman V;Ong CK;Paulini M;Pedro H;Perry E;Russell M;Sparrow H;Tapanari E;Taylor K;Vullo A;Williams G;Zadissia A;Olson A;Stein J;Wei S;Tello-Ruiz M;Ware D;Luciani A;Potter S;Finn RD;Urban M;Hammond-Kosack KE;Bolser DM;De Silva N;Howe KL;Langridge N;Maslen G;Staines DM;Yates A
• 通讯作者: Yates A

Ensembl Genomes 2016: more genomes, more complexity.

• DOI: 10.1093/nar/gkv1209
• 发表时间: 2016-01-04
• 期刊: Nucleic acids research
• 影响因子: 14.9
• 作者: Kersey PJ;Allen JE;Armean I;Boddu S;Bolt BJ;Carvalho-Silva D;Christensen M;Davis P;Falin LJ;Grabmueller C;Humphrey J;Kerhornou A;Khobova J;Aranganathan NK;Langridge N;Lowy E;McDowall MD;Maheswari U;Nuhn M;Ong CK;Overduin B;Paulini M;Pedro H;Perry E;Spudich G;Tapanari E;Walts B;Williams G;Tello-Ruiz M;Stein J;Wei S;Ware D;Bolser DM;Howe KL;Kulesha E;Lawson D;Maslen G;Staines DM
• 通讯作者: Staines DM

Triticeae resources in Ensembl Plants.

• DOI: 10.1093/pcp/pcu183
• 发表时间: 2015-01
• 期刊: Plant & cell physiology
• 影响因子: 4.9
• 作者: Bolser DM;Kerhornou A;Walts B;Kersey P
• 通讯作者: Kersey P