Investigation and manipulation of mTOR cellular signalling to generate novel CHO host cells with high growth and productivity characteristics
Investigation and manipulation of mTOR cellular signalling to generate novel CHO host cells with high growth and productivity characteristics
批准号:
BB/J007714/1
负责人:
Christopher Proud
金额:
$41.99万
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2012
资助国家:
英国
项目状态:
已结题
起止时间:
2012 至 --
中文摘要
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英文摘要
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Crosstalk between mTOR complexes
mTOR 复合物之间的串扰
DOI:
10.1038/ncb2877
发表时间:
2013
期刊:
Nature Cell Biology
影响因子:
21.3
作者:
[Xie J]
通讯作者:
Xie J
Constitutively-active Rheb mutants [T23M] and [E40K] drive increased production and secretion of recombinant protein in Chinese hamster ovary cells
组成型活性 Rheb 突变体 [T23M] 和 [E40K] 驱动中国仓鼠卵巢细胞中重组蛋白的产生和分泌增加
DOI:
10.22541/au.160218204.42443382/v1
发表时间:
2020
期刊:
影响因子:
--
作者:
[Poi S]
通讯作者:
Poi S
Elongation factor 2 kinase promotes cell survival by inhibiting protein synthesis without inducing autophagy.
伸长因子2激酶通过抑制蛋白质合成而无需诱导自噬来促进细胞存活。
DOI:
10.1016/j.cellsig.2016.01.005
发表时间:
2016-04
期刊:
Cellular signalling
影响因子:
4.8
作者:
[Moore CE, Wang X, Xie J, Pickford J, Barron J, Regufe da Mota S, Versele M, Proud CG]
通讯作者:
Proud CG
DOI:
10.1042/bcj20160845
发表时间:
2016-12-15
期刊:
The Biochemical journal
影响因子:
--
作者:
[Jossé L, Xie J, Proud CG, Smales CM]
通讯作者:
Smales CM
High Resolution Mass Spectrometer to support Proteomic Research across the Southern 4 Proteomic Consortium
-
批准号:BB/M012387/1
-
项目类别:Research Grant
-
资助金额:$57.17万
-
财政年份:2015
-
负责人:Christopher Proud
-
依托单位:
eIF2B (eukaryotic initiation factor 2B): regulation of its activity and expression, and its roles in translation initiation
-
批准号:BB/J007706/1
-
项目类别:Research Grant
-
资助金额:$78.57万
-
财政年份:2012
-
负责人:Christopher Proud
-
依托单位:
Southampton-Shanghai partnership for the posttranscriptional control of mammalian gene expression
-
批准号:BB/H531619/1
-
项目类别:Research Grant
-
资助金额:$3.03万
-
财政年份:2010
-
负责人:Christopher Proud
-
依托单位:
A Systems Biological Approach to Elucidate Local Protein Synthesis Code in Plasticity and Memory
-
批准号:BB/I004483/1
-
项目类别:Research Grant
-
资助金额:$32.99万
-
财政年份:2010
-
负责人:Christopher Proud
-
依托单位:
Regulation and structural organisation of a key regulatory translation factor eIF2B
-
批准号:BB/G008396/1
-
项目类别:Research Grant
-
资助金额:$84.15万
-
财政年份:2009
-
负责人:Christopher Proud
-
依托单位:
国内基金
海外基金
冷原子系统自旋压缩的理论研究
-
批准号:10804007
-
项目类别:青年科学基金项目
-
资助金额:17.0万元
-
批准年份:2008
-
负责人:金光日
-
依托单位: