Function and application of novel proteins from sponge symbionts

海绵共生体新型蛋白质的功能和应用

• 批准号: DP180100552
• 负责人: Prof Torsten Thomas
• 金额: $ 0.39万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-06-01 至 2019-10-15
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP180100552
• 关键词: Function; application; novel; proteins; sponge

This project aims to determine the function of eukaryotic-like proteins (ELPs) from bacterial symbionts of sponges and apply this knowledge to develop new tools for biotechnology. This project will use innovative microscopy techniques and gene expression studies to define the molecular and cellular interactions of ELPs with sponges and how this is influenced by changing environmental conditions. ELPs will be further used to create new, artificial interactions between bacteria and eukaryotes. This project will provide fundamental knowledge on the evolution and function of newly discovered ELPs found in both beneficial and pathogenic bacteria and paves the way to control symbiosis for biotechnological applications.

本项目旨在确定海绵细菌共生体中真核样蛋白（ELPs）的功能，并将这些知识应用于开发新的生物技术工具。该项目将使用创新的显微镜技术和基因表达研究来确定elp与海绵的分子和细胞相互作用，以及这种相互作用如何受到不断变化的环境条件的影响。elp将进一步用于在细菌和真核生物之间创造新的人工相互作用。该项目将为研究有益菌和致病菌中新发现的elp的进化和功能提供基础知识，并为生物技术应用控制共生铺平道路。