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SYNTHESIS AND REACTIONS OF NOVEL HETEROCYCLES

SYNTHESIS AND REACTIONS OF NOVEL HETEROCYCLES
新型杂环化合物的合成和反应
批准号：
3165113
负责人：
OLIVIER R MARTIN
金额：
$9.35万
依托单位：
STATE UNIVERSITY OF NY,BINGHAMTON
依托单位国家：
美国
项目类别：
财政年份：
1979
资助国家：
美国
项目状态：
已结题
起止时间：
1979-06-01 至 1986-11-30
来源：
https://reporter.nih.gov/project-details/3165113
关键词：
acylation amino group azides bicyclic compound carbanion chemical group chemical synthesis conformation drug design /synthesis /production gas chromatography heterocyclic compounds nitrogenous heterocyclic compound nuclear magnetic resonance spectroscopy triazines

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中文摘要
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英文摘要
Synthetic procedures will be developed to introduce functional groups in simple and complex molecules. The chemistry, in particular cycloadditions, of small ring heterocycles will be investigated. Methods of synthesis and new heterocyclic systems will be developed and their chemistry studied. The stereochemistry, conformational analysis and mechanisms of these reactions will be investigated. Stereochemistry of reactions in four-membered ring and their ring expansion will be studied. Some of these compounds are of interest as potential anticancer agents.
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SMALL INSTRUMENTATION PROGRAM
INTRAMOLECULAR C-GLYCOSIDATION OF SUBSTITUTED SUGARS
INTRAMOLECULAR C-GLYCOSIDATION OF SUBSTITUTED SUGARS
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