A STUDY OF AGE-RELATED DIFFERENCES IN CANCER MANAGEMENT

该研究项目旨在评估以下因素 从患者的角度区分老年和年轻患者群体 管理程序已被证明可减少发病率和 女性乳腺癌和直肠癌死亡率。考虑到 年轻的白人乳腺癌患者在1，3 或与年龄较大的年龄组相比5年相对存活率，并考虑到 年轻的白人女性直肠癌患者的发病率在15%到20%之间 与老年患者相比，它的1年、3年和5年相对生存率更高 提示在预测中可能存在系统差异 重要的患者管理程序，提供给和/或 直肠癌可能不存在或存在到 乳腺癌的范围较小。鉴于这两种疾病的发病率都有所增加 老年人中的癌症，以及年龄似乎扮演的不同角色 关于两个地点之间的生存，极其重要的是 了解患者管理和行为因素在 与疾病和宿主特征的关系，对护理模式有影响 适用于特定人群的中老年女性癌症患者。 纪念斯隆-凯特琳癌症中心与New 纽约州卫生部、康奈尔大学医学中心和 国家民意研究中心，建议通过以下方式评估这些问题 确定了纽约市白人女性患者的代表性样本， 45岁及以上，患有乳腺癌或直肠癌，采访这些人 患者和每个患者指定的一名支持人员，获得临床 从患者的医疗记录和患者的医生那里获得的数据 并分析这些数据以确定年龄变量的影响， 治疗前选择的社会经济地位和患病地点， 治疗选择和后续护理由医生提供，并由 病人。

This research project has been designed to evaluate factors that differentiate older from younger patient groups in terms of patient management procedures that have been shown to reduce the morbidity and mortality from breast cancer and rectal cancer in females. Given that younger white breast cancer patients do not experience differences in 1, 3 or 5 year relative survival compared with older age groups, and given that younger white female rectal cancer patients experience between 15 and 20% higher 1, 3, and 5 year relative survival compared with older patients, it is suggested that systematic differences may exist in prognostically significant patient management procedures, that are offered to and/or accepted by women with rectal cancer, which may not exist or exist to a lesser extent for breast cancer. Given the increased incidence of both cancers among the elderly, and the different role age seems to play with respect to survival between the two sites, it is extremely important to understand the impact that patient management and behavioral factors, in relation to disease and host characteristics, have on the patterns of care for a defined population of middle-aged and elderly female cancer patients. The Memorial Sloan-Kettering Cancer Center in collaboration with the New York State Department of Health, Cornell University Medical Center and the National Opinion Research Center, proposes to evaluate these issues by identifying a representative sample of New York City white female patients, 45 and older, with cancers of the breast or rectum, interviewing these patients and a support person named by each patient, obtaining clinical data from the patients' medical records and from the patients' physicians and analyzing these data to determine the effects of the variables of age, socio-economic status and site of disease on pre-treatment choices, treatment choices and follow-up care offered by the physician and chosen by the patient.