eHive-RPC: A Remote Procedure Call Public Interface for eHive
eHive-RPC: A Remote Procedure Call Public Interface for eHive
批准号:
BB/M020398/1
负责人:
Paul Flicek
金额:
$16.82万
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2015
资助国家:
英国
项目状态:
已结题
起止时间:
2015 至 --
中文摘要
点击翻译按钮获取中文摘要
英文摘要
Ensembl developed 'eHive' as a production system that manages and optimizes the running of tasks (called 'jobs'), on a compute cluster that may have thousands of Central Processing Units (CPUs). A CPU is the hardware within a computer that carries out the instructions of a computer program by performing the basic input and output operations of the system. Each computer has one or more CPUs.Some compute clusters comprise many thousands of CPUs distributed amongst many computers. With so many computers and CPUs, it is important that jobs are sent to these CPUs in a fair and efficient manner, especially when many users are competing to use the same resources. Clusters usually rely on a central queuing system that holds a list of all the jobs that need to be run and can give individual computers in the cluster explicit instructions about which job to execute. This type of queuing system works well if the jobs each take an hour or more to complete. However, when jobs complete faster than they can be scheduled it creates a processing bottleneck e.g. if a job executes in minutes or less. The usual way to solve the bottleneck is to implement another system on top of the scheduler that 'batches' similar jobs together to make operations more efficient.eHive's novel solution to the issue of job queuing is to move away from this central job scheduling: eHive is a 'distributed' processing system based on 'autonomous agents' with the behavioural structure of honeybees, hence the term 'eHive'. eHive maintains the ability to monitor and track jobs via a central 'blackboard'. Workers are efficiently created on a compute cluster, known as a meadow, with no specific task assigned to them. Once running, each worker contacts the blackboard, is able to find the most suitable kind of job, specializes to claim work and runs multiple jobs of this type in a row. Workers are able to re-specialize to claim other types of jobs once they exhaust their original designation. Each worker regularly updates its status in the blackboard to allow other workers to optimize the overall job distribution.The benefits of eHive are (a) a reduction in the overhead of individual job processing, (b) an increase in the maximum number of tasks that can be running at any one time, (c) an increase in the tolerance to faults in the compute cluster, and (d) the allowance of complicated processes running in parallel.Although eHive was originally designed for the purpose of Ensembl, its functionality is applicable to all data types that have large compute requirements. In this project we aim to transform the possibilities of eHive further, by developing a 'Remote Procedure Call system (RPC) for eHive. This will allow jobs to run on remote clusters as well as local clusters, thereby expanding the use of eHive to multiple compute clusters and cloud computing services. This will enable wider use of eHive within data-intensive fields in the life sciences and beyond.
期刊论文(7)
专著(0)
科研奖励(0)
会议论文
登录
查看更多内容
DOI:
10.1093/nar/gkaa942
发表时间:
2021-01-08
期刊:
Nucleic acids research
影响因子:
14.9
作者:
[Howe KL, Achuthan P, Allen J, Allen J, Alvarez-Jarreta J, Amode MR, Armean IM, Azov AG, Bennett R, Bhai J, Billis K, Boddu S, Charkhchi M, Cummins C, Da Rin Fioretto L, Davidson C, Dodiya K, El Houdaigui B, Fatima R, Gall A, Garcia Giron C, Grego T, Guijarro-Clarke C, Haggerty L, Hemrom A, Hourlier T, Izuogu OG, Juettemann T, Kaikala V, Kay M, Lavidas I, Le T, Lemos D, Gonzalez Martinez J, Marugán JC, Maurel T, McMahon AC, Mohanan S, Moore B, Muffato M, Oheh DN, Paraschas D, Parker A, Parton A, Prosovetskaia I, Sakthivel MP, Salam AIA, Schmitt BM, Schuilenburg H, Sheppard D, Steed E, Szpak M, Szuba M, Taylor K, Thormann A, Threadgold G, Walts B, Winterbottom A, Chakiachvili M, Chaubal A, De Silva N, Flint B, Frankish A, Hunt SE, IIsley GR, Langridge N, Loveland JE, Martin FJ, Mudge JM, Morales J, Perry E, Ruffier M, Tate J, Thybert D, Trevanion SJ, Cunningham F, Yates AD, Zerbino DR, Flicek P]
通讯作者:
Flicek P
DOI:
10.1093/nar/gkab1049
发表时间:
2022-01-07
期刊:
Nucleic acids research
影响因子:
14.9
作者:
[Cunningham F, Allen JE, Allen J, Alvarez-Jarreta J, Amode MR, Armean IM, Austine-Orimoloye O, Azov AG, Barnes I, Bennett R, Berry A, Bhai J, Bignell A, Billis K, Boddu S, Brooks L, Charkhchi M, Cummins C, Da Rin Fioretto L, Davidson C, Dodiya K, Donaldson S, El Houdaigui B, El Naboulsi T, Fatima R, Giron CG, Genez T, Martinez JG, Guijarro-Clarke C, Gymer A, Hardy M, Hollis Z, Hourlier T, Hunt T, Juettemann T, Kaikala V, Kay M, Lavidas I, Le T, Lemos D, Marugán JC, Mohanan S, Mushtaq A, Naven M, Ogeh DN, Parker A, Parton A, Perry M, Piližota I, Prosovetskaia I, Sakthivel MP, Salam AIA, Schmitt BM, Schuilenburg H, Sheppard D, Pérez-Silva JG, Stark W, Steed E, Sutinen K, Sukumaran R, Sumathipala D, Suner MM, Szpak M, Thormann A, Tricomi FF, Urbina-Gómez D, Veidenberg A, Walsh TA, Walts B, Willhoft N, Winterbottom A, Wass E, Chakiachvili M, Flint B, Frankish A, Giorgetti S, Haggerty L, Hunt SE, IIsley GR, Loveland JE, Martin FJ, Moore B, Mudge JM, Muffato M, Perry E, Ruffier M, Tate J, Thybert D, Trevanion SJ, Dyer S, Harrison PW, Howe KL, Yates AD, Zerbino DR, Flicek P]
通讯作者:
Flicek P
DOI:
10.1093/nar/gkw1104
发表时间:
2017-01-04
期刊:
Nucleic acids research
影响因子:
14.9
作者:
[Aken BL, Achuthan P, Akanni W, Amode MR, Bernsdorff F, Bhai J, Billis K, Carvalho-Silva D, Cummins C, Clapham P, Gil L, Girón CG, Gordon L, Hourlier T, Hunt SE, Janacek SH, Juettemann T, Keenan S, Laird MR, Lavidas I, Maurel T, McLaren W, Moore B, Murphy DN, Nag R, Newman V, Nuhn M, Ong CK, Parker A, Patricio M, Riat HS, Sheppard D, Sparrow H, Taylor K, Thormann A, Vullo A, Walts B, Wilder SP, Zadissa A, Kostadima M, Martin FJ, Muffato M, Perry E, Ruffier M, Staines DM, Trevanion SJ, Cunningham F, Yates A, Zerbino DR, Flicek P]
通讯作者:
Flicek P
DOI:
10.1093/nar/gkx1098
发表时间:
2018-01-04
期刊:
Nucleic acids research
影响因子:
14.9
作者:
[Zerbino DR, Achuthan P, Akanni W, Amode MR, Barrell D, Bhai J, Billis K, Cummins C, Gall A, Girón CG, Gil L, Gordon L, Haggerty L, Haskell E, Hourlier T, Izuogu OG, Janacek SH, Juettemann T, To JK, Laird MR, Lavidas I, Liu Z, Loveland JE, Maurel T, McLaren W, Moore B, Mudge J, Murphy DN, Newman V, Nuhn M, Ogeh D, Ong CK, Parker A, Patricio M, Riat HS, Schuilenburg H, Sheppard D, Sparrow H, Taylor K, Thormann A, Vullo A, Walts B, Zadissa A, Frankish A, Hunt SE, Kostadima M, Langridge N, Martin FJ, Muffato M, Perry E, Ruffier M, Staines DM, Trevanion SJ, Aken BL, Cunningham F, Yates A, Flicek P]
通讯作者:
Flicek P
DOI:
10.1093/nar/gky1113
发表时间:
2019-01-08
期刊:
Nucleic acids research
影响因子:
14.9
作者:
[Cunningham F, Achuthan P, Akanni W, Allen J, Amode MR, Armean IM, Bennett R, Bhai J, Billis K, Boddu S, Cummins C, Davidson C, Dodiya KJ, Gall A, Girón CG, Gil L, Grego T, Haggerty L, Haskell E, Hourlier T, Izuogu OG, Janacek SH, Juettemann T, Kay M, Laird MR, Lavidas I, Liu Z, Loveland JE, Marugán JC, Maurel T, McMahon AC, Moore B, Morales J, Mudge JM, Nuhn M, Ogeh D, Parker A, Parton A, Patricio M, Abdul Salam AI, Schmitt BM, Schuilenburg H, Sheppard D, Sparrow H, Stapleton E, Szuba M, Taylor K, Threadgold G, Thormann A, Vullo A, Walts B, Winterbottom A, Zadissa A, Chakiachvili M, Frankish A, Hunt SE, Kostadima M, Langridge N, Martin FJ, Muffato M, Perry E, Ruffier M, Staines DM, Trevanion SJ, Aken BL, Yates AD, Zerbino DR, Flicek P]
通讯作者:
Flicek P
共 6 条
Ensembl - adding value to animal genomes through high quality annotation
-
批准号:BB/S020152/1
-
项目类别:Research Grant
-
资助金额:$48.22万
-
财政年份:2019
-
负责人:Paul Flicek
-
依托单位:
The Animal Functional Genomics Resource
-
批准号:BB/N019563/1
-
项目类别:Research Grant
-
资助金额:$69.28万
-
财政年份:2016
-
负责人:Paul Flicek
-
依托单位:
Ensembl genome portal for farm and companion animals
-
批准号:BB/M011615/1
-
项目类别:Research Grant
-
资助金额:$52.74万
-
财政年份:2015
-
负责人:Paul Flicek
-
依托单位:
COpenPlantOmics (COPO): a Collaborative Bioinformatics Plant Science Platform
-
批准号:BB/L024071/1
-
项目类别:Research Grant
-
资助金额:$10.96万
-
财政年份:2014
-
负责人:Paul Flicek
-
依托单位:
Ensembl and enabling genetics and genomics research in farmed animal species
-
批准号:BB/I025506/1
-
项目类别:Research Grant
-
资助金额:$33.08万
-
财政年份:2012
-
负责人:Paul Flicek
-
依托单位:
Detecting signatures of natural selection in the human genome with geographically explicit models
-
批准号:BB/H008691/1
-
项目类别:Research Grant
-
资助金额:$18.72万
-
财政年份:2010
-
负责人:Paul Flicek
-
依托单位:
国内基金
海外基金
登录
查看更多内容
顺铂联合重组蛋白rPC 在头颈部鳞癌治疗中的增效作用及机制研究
-
批准号:LY23H130002
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2023
-
负责人:陈鸣
-
依托单位:
RPC激活Müller细胞CNTF/STAT3/TSP-1通路重启RP植入干细胞后突触形成的机制研究
-
批准号:
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2022
-
负责人:何翔宇
-
依托单位:
预制CFRP-不锈钢筋RPC管约束海砂混凝土组合柱的复合约束效应控制与设计方法研究
-
批准号:52178122
-
项目类别:面上项目
-
资助金额:58万元
-
批准年份:2021
-
负责人:王志滨
-
依托单位:
RPC加固混凝土框架动态性能与抗爆设计方法研究
-
批准号:52078169
-
项目类别:面上项目
-
资助金额:58.0万元
-
批准年份:2020
-
负责人:侯晓萌
-
依托单位:
蛋白激酶RPC在番茄与辣椒疫霉互作中的作用和机理
-
批准号:32072399
-
项目类别:面上项目
-
资助金额:58.0万元
-
批准年份:2020
-
负责人:张美祥
-
依托单位:
RPC2调控玉米籽粒发育的分子机制
-
批准号:31971951
-
项目类别:面上项目
-
资助金额:58.0万元
-
批准年份:2019
-
负责人:邱法展
-
依托单位:
U形RPC预制梁外壳装配整体式框架结构性能与设计研究
-
批准号:51878128
-
项目类别:面上项目
-
资助金额:60.0万元
-
批准年份:2018
-
负责人:鞠彦忠
-
依托单位:
预应力RPC-RC柔性节段桩基础整体无缝桥的受荷性状和设计计算方法研究
-
批准号:51778147
-
项目类别:面上项目
-
资助金额:56.0万元
-
批准年份:2017
-
负责人:庄一舟
-
依托单位:
面向远洋岛礁工程的RPC-FRP预制管组合柱基本性能研究
-
批准号:51678228
-
项目类别:面上项目
-
资助金额:62.0万元
-
批准年份:2016
-
负责人:单波
-
依托单位:
高强钢管-活性粉末混凝土(RPC)组合柱约束机理及力学性能研究
-
批准号:51578156
-
项目类别:面上项目
-
资助金额:61.0万元
-
批准年份:2015
-
负责人:韦建刚
-
依托单位: